6 documents found, page 1 of 1
Biophysical analyses of the HRSV NS2 protein: insights about its interaction wi...
Lourenco, Isabella O. de [UNESP]; Sa, Jessica M. de [UNESP]; Miranda, Artemiza S. [UNESP]; Caruso, Icaro P. [UNESP]; Fossey, Marcelo A. [UNESP]Made available in DSpace on 2022-04-28T17:23:14Z (GMT). No. of bitstreams: 0 Previous issue date: 2022-02-11; Univ Estadual Paulista UNESP, Phys, Sao Jose Do Rio Preto, Brazil; UNESP, Multiuser Ctr Biomol Innovat, Sao Jose Do Rio Preto, Brazil; Univ Fed Rio de Janeiro, Rio De Janeiro, Brazil; Univ Estadual Paulista UNESP, Phys, Sao Jose Do Rio Preto, Brazil; UNESP, Multiuser Ctr Biomol Innovat, Sao Jose Do Rio ...
Hesperetin targets the hydrophobic pocket of the nucleoprotein/phosphoprotein b...
Sá, Jéssica M. [UNESP]; Piloto, João V. [UNESP]; Cilli, Eduardo M. [UNESP]; Tasic, Ljubica; Fossey, Marcelo A. [UNESP]; Almeida, Fábio C. L.Made available in DSpace on 2021-06-25T10:36:42Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-01-01; The human Respiratory Syncytial Virus (hRSV) is one of the most common causes of acute respiratory diseases such as bronchiolitis and pneumonia in children worldwide. Among the viral proteins, the nucleoprotein (N) stands out for forming the nucleocapsid (NC) that functions as a template for replication...
Biophysical and Dynamic Characterization of Fine-Tuned Binding of the Human Res...
Caruso, Icaro P. [UNESP]; Guimarães, Giovana C. [UNESP]; Machado, Vitor B. [UNESP]; Fossey, Marcelo A. [UNESP]; Willbold, Dieter; Almeida, Fabio C.L.Made available in DSpace on 2021-06-25T10:44:23Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-12-01; The human respiratory syncytial virus (hRSV) M2-1 protein functions as a processivity and antitermination factor of the viral polymerase complex. Here, the first evidence that the hRSV M2-1 core domain (cdM2-1) alone has an unfolding activity for long RNAs is presented and the biophysical and dynamic ch...
Thermodynamic profile and molecular modeling of the interaction between Grb2 di...
Sanches, Karoline [UNESP]; Dias, Raphael V.R. [UNESP]; da Silva, Paulo H. [UNESP]; Caruso, Icaro P. [UNESP]; Fossey, Marcelo A. [UNESP]Made available in DSpace on 2021-06-25T10:54:33Z (GMT). No. of bitstreams: 0 Previous issue date: 2021-06-15; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); The adaptor protein growth factor-bound protein 2 (Grb2) is an important regulator of the fibroblast growth factor receptor 2 (FGFR2) before extracellular stimuli. It is k...
Insights into interactions of flavanones with target human respiratory syncytia...
Piva, Hêmily M. R. [UNESP]; Sá, Jéssica M. [UNESP]; Miranda, Artemiza S. [UNESP]; Tasic, Ljubica; Fossey, Marcelo A. [UNESP]; Souza, Fátima P. [UNESP]Made available in DSpace on 2020-12-12T02:00:41Z (GMT). No. of bitstreams: 0 Previous issue date: 2020-03-02; Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Fundação de Amparo à Pesquisa do Estado do Rio de Janeiro (FAPERJ); The human Respiratory Syncytial Virus (hRSV) is the most frequent agent of respiratory infections in infants and children with no currently approved vaccine. The M2-1 protei...
Binding investigation between M2-1protein from hRSV and acetylated quercetin de...
Guimarães, Giovana C. [UNESP]; Piva, Hemily R.M. [UNESP]; Araújo, Gabriela C. [UNESP]; Lima, Caroline S. [UNESP]; Regasini, Luis O. [UNESP]Made available in DSpace on 2018-12-11T17:17:14Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-05-01; The human Respiratory Syncytial Virus (hRSV) is the main responsible for occurrences of respiratory diseases as pneumonia and bronchiolitis in children and elderly. M2-1 protein from hRSV is an important antitermination factor for transcription process that prevents the premature dissociation of the pol...