Oral squamous papilloma is a benign neoplasm of epithelial origin, quite common, associated with infection by the Human Papilloma Virus (HPV). Clinically, it presents as an exophytic nodule, soft, painless and generally pedunculated, with a verrucous / papillomatous aspect. This study aims to report a case of a patient with a clinical and histopathological diagnosis of large oral squamous papilloma, with foci o...