6 documents found, page 1 of 1
Rehabilitation of a Child with Neonatal Brachial Plexus Palsy: Case Report Desc...
Frade, F; Neves, L; Florindo-Silva, F; Gómez-Salgado, J; Jacobsohn, L; Frade, JThis paper presents a case report of a child with Neonatal Brachial Plexus Palsy on the right arm, with C5, C6, and C7 nerve injuries. The symptoms presented at birth and at the time of diagnosis were absence of movement in the right arm but with mobility of the fingers; internal rotation of the injured limb with elbow extension; active flexion of the wrist and fingers; and ulnar deviation of the hand. The reha...
EGFR Assessment in Lung Cancer CT Images: Analysis of Local and Holistic Region...
Silva, F; Pereira, T; Morgado, J; Frade, J; Mendes, J; Freitas, C; Negrao, E; Lima, BF; Silva, M; Madureira, AJ; Ramos, I; Hespanhol, V; Costa, JLStatistics have demonstrated that one of the main factors responsible for the high mortality rate related to lung cancer is the late diagnosis. Precision medicine practices have shown advances in the individualized treatment according to the genetic profile of each patient, providing better control on cancer response. Medical imaging offers valuable information with an extensive perspective of the cancer, openi...
Pharmacogenetics of advanced lung cancer: Predictive value of functional geneti...
Catarata, MJ; Lourenço, M; Martins, MF; Frade, J; Pêgo, A; Cordeiro, CR; Medeiros, R; Ribeiro, RIntroduction: AGXT gene codes for the enzyme alanine glyoxylate aminotransferase, which is involved in hepatic peroxisomal metabolism of platinum-based chemotherapeutic agents. The association of genetic variant AGXT rs34116584 on the clinical outcome and response to chemotherapy of patients with non-small cell lung cancer (NSCLC) remains to be established. Our aim was to evaluate the association of functional ...
Pre-training autoencoder for lung nodule malignancy assessment using CT images
Silva, F; Pereira, T; Frade, J; Mendes, J; Freitas, C; Hespanhol, V; Costa, JL; Cunha, A; Oliveira, HPLung cancer late diagnosis has a large impact on the mortality rate numbers, leading to a very low five-year survival rate of 5%. This issue emphasises the importance of developing systems to support a diagnostic at earlier stages. Clinicians use Computed Tomography (CT) scans to assess the nodules and the likelihood of malignancy. Automatic solutions can help to make a faster and more accurate diagnosis, which...
Adult-onset autoimmune diabetes: comparative analysis of classical and latent p...
Fadiga, L; Saraiva, J; Catarino, D; Frade, J; Melo, M; Paiva, IIntroduction: Adult-onset autoimmune diabetes (AID) has two different phenotypes: classic type 1 diabetes mellitus (T1DM), with insulin requirement just after diagnosis, and latent autoimmune diabetes in adults (LADA). The purpose of this study is to characterize patients with AID followed on a tertiary centre, comparing classic T1DM and LADA. Methods: We collected data from patients with diabetes and positive ...
Obras de Grão Vasco e da sua Oficina
Maia, B; Frade, J; Calvo, A; Candeias, A; Mirão, J; Cardoso, AThis study focuses on the work of one of the main Portuguese painters from the 16th century, Vasco Fernandes also known as Grão Vasco.For comparative purposes, are addressed in this paper the following paintings attributed to Vasco Fernandes, using different criteria: the São Pedro (awarded in 1607 by Luis Pereira, minister of Viseu’s cathedral), the Tríptico de Cook (signed), the Assunção da Virgem (given alon...