4 documents found, page 1 of 1
Pericardial NT-Pro-BNP and GDF-15 as Biomarkers of Atrial Fibrillation and Atri...
Fragão-Marques, M; Barroso, I; Farinha, R; Miranda, IM; Martins, D; Mancio, J; Rocha-Neves, J; Guimarães, JT; Leite-Moreira, A; Falcão-Pires, IAims: This study aimed to evaluate the association of GDF-15 and NT-pro-BNP in two different biological matrices with AF in severe aortic stenosis patients undergoing aortic valve replacement surgery (AVR), its association with atrial matrix remodeling, as well as with 30-day postoperative outcomes. Main Methods: One hundred and twenty-six patients between 2009 and 2019 with severe aortic stenosis undergoing AV...
Inflammatory response assessment in patients with COVID-19 under extracorporeal...
Fragão-Marques, M; Barroso, I; Loureiro, H; Duarte-Gamas, L; Pinheiro, D; Guimarães, JT"Background: Extracorporeal membrane oxygenation (ECMO), could be extremely helpful in the management of COVID-19 patients with refractory hypoxemic respiratory failure; however, to date, evidence on the true effecttiveness of ECMO in the COVID19 setting still hangs in the balance. Methods: This was a prospective cohort study of 39 COVID-19 patients admitted to the intensive care unit (ICU) in an experienced EC...
Atrial matrix remodeling in atrial fibrillation patients with aortic stenosis
Fragão-Marques, M; Miranda, I; Martins, D; Barroso, I; Mendes, C; Pereira-Neves, A; Falcão-Pires, I; Leite-Moreira, ABackground. This study aimed to evaluate atrium extracellular matrix remodeling in atrial fibrillation (AF) patients with severe aortic stenosis, through histological fibrosis quantification and extracellular matrix gene expression analysis, as well as serum quantification of selected protein targets. Methods. A posthoc analysis of a prospective study was performed in a cohort of aortic stenosis patients. Betwe...
Meta-Analysis of Relation of Epicardial Adipose Tissue Volume to Left Atrial Di...
Mancio, J; Azevedo, D; Fragão-Marques, M; Falcão-Pires, I; Leite-Moreira, A; Lunet, N; Fontes-Carvalho, R; Bettencourt, NMany studies have explored the hypothesis that epicardial adipose tissue (EAT) accumulation adversely affects cardiac remodeling. We assessed, through a systematic review and meta-analysis, whether EAT is linked to left atrial (LA) and left ventricular (LV) structure and function, irrespective of global or abdominal visceral adiposity. We searched MEDLINE, Scopus, and Web of Science for studies evaluating the a...