3 documents found, page 1 of 1
Neuropharmacological and genotoxic evaluation of ethanol extract from Erythrina...
Dias,Simone A.; Neves,Aline E. O.; Ferraz,Alexandre de B. F.; Picada,Jaqueline N.; Pereira,PatríciaThe aim of the present study was to determine neurobehavioral and genotoxic activities of ethanol extract of Erythrina falcata Benth., Fabaceae, leaves on rats. Animals were treated with ethanol extract of E. falcata (100, 300 or 500 mg/kg; i.p.) and the open field and elevated plus-maze tasks were used as behavioral models to investigate a possible effect on the locomotor and exploratory activity and anxiety, ...
The antigenotoxic activity of latex from Himatanthus articulatus
Rebouças,Sebastião de O.; Silva,Juliana da; Groff,Aline A.; Nunes,Emilene A.; Ianistcki,Martus; Ferraz,Alexandre de B. F.Himatanthus articulatus (Vahl) Woodson (Apocynaceae) is a native plant to the Amazon popularly used to treat ulcers, tumors, inflammations, cancer, syphilis and malaria. The aim of the present study was to investigate the in vivo genotoxic/antigenotoxic and mutagenic potential of this plant, using the comet and the micronucleus assays in mice. Female and male adult mice were treated with different doses of H. a...
Evaluation of effects of dichloromethane fraction from Platonia insignis on pil...
Costa Júnior,Joaquim S. da; Ferraz,Alexandre de B. F.; Feitosa,Chistiane Mendes; Citó,Antonia Maria das Graças Lopes; Saffi,JeniferThe objective of present study was to evaluate the antioxidant and anticonvulsant activities of dichloromethane fraction (DMF) from Platonia insignis Mart., Clusiaceae. The DMF from P. insignis (2 mg/kg) was tested by intraperitoneal (i.p.) to evaluate effects on lipid peroxidation level, nitrite formation, as well as on locomotor and anticonvulsant activities. Wistar rats were treated with, (saline/Tween 80 0....