3 documents found, page 1 of 1
Very late presentation of a disorder of sex development
Martins, J.M.; Fraga, M.; Miguens, J.; Tortosa, F.; Marques, B.; Sousa, A.D.Disorders of sex development generally present in the neonatal period with ambiguity of external genitalia. We report a very old male patient presenting at 75 years because of panhypopituitarism and a large nonsecreting pituitary macroadenoma secondary to long-standing primary hypogonadism due to 46,XX sex reversal disorder now first diagnosed. Sex development disorders may go unrecognised for the entire life s...
Very late presentation of a disorder of sex development
Martins, João Martin; Fraga, M.; Miguens, J.; Tortosa, F.; Marques, Bárbara; Sousa, A. D.Disorders of sex development generally present in the neonatal period with ambiguity of external genitalia. We report a very old male patient presenting at 75 years because of panhypopituitarism and a large nonsecreting pituitary macroadenoma secondary to long-standing primary hypogonadism due to 46,XX sex reversal disorder now first diagnosed. Sex development disorders may go unrecognised for the entire life s...
Simultaneous determination of Deoxynivalenol, Deoxynivalenol-3-Glucoside and Ni...
Trombete, F.; Barros, A.; Vieira, Madalena; Saldanha, Tatiana; Venâncio, Armando; Fraga, M.Deoxynivalenol-3-glucoside (D3G) is a modified mycotoxin formed by the metabolism of plants through the conjugation of deoxynivalenol (DON) with glucose. Toxicology studies of D3G for human and animal health are still under investigation, and the development of practical and reliable methods for its direct determination, especially in cereal matrices, is of great importance. In the present study, a methodology ...