4 documents found, page 1 of 1
HER2 Status in RAS and BRAF Wild-Type Metastatic Colorectal Cancer: A Portugues...
Fraga, Teresa; Sousa, Maria João; Magalhães, Joana; Basto, Raquel; Paulo, Judy; Bonito, Nuno; Magalhães, José Paulo; Figueiredo, PauloIntroduction: Colorectal cancer (CRC) is the second-most deadly cancer worldwide. However, there remains a scarcity of precision treatments available for this type of cancer. Amplification or overexpression of human epidermal growth factor receptor 2 (HER2+) is a well-established therapeutic target in gastric and breast cancer. HER2 is positive in approximately 5% of CRC cases and has been implicated in resista...
Adjuvant Hyperthermic Intravesical Chemotherapy in Intermediate- and High-Risk ...
Magalhães, Joana C; Sousa, Maria João; Basto, Raquel; Fraga, Teresa; Gomes, Inês; Fernandes, Catarina; Mariano, Mónica; Paulo, Judy; Madeira, PedroIntroduction: Non-muscle invasive bladder cancer (NMIBC) is a frequently diagnosed neoplasm, which is typically managed with transurethral resection of bladder tumor (TURBT) eventually followed by intravesical therapies. Bacillus Calmette-Guérin (BCG) is used as first-line adjuvant treatment in high- (HR) and intermediate-risk (IR) NMIBC, although, in the latter, mitomycin C (MMC) may also be used. Multiple lim...
Consensus Guidelines for the Management of Abnormal Cervical Cancer Screening T...
Pedro, Amélia; Pacheco, Amália; Sousa , Rita; Mendinhos, Gustavo; Miranda, Mariana; Urzal, Cecília; Monteiro, Virgínia; Fraga, TeresaCervical cancer is one of the most common types of cancer in women. Cervical cancer screening is needed for the detection and treatment of cervical neoplastic lesions that can evolve to neoplasia and to reduce the incidence of cervical cancer. Recently, changes were made to increase the efficiency of the screening process such as employing the human papilloma virus detection test as the gold standard for cervic...
Orientações de consenso para a abordagem dos resultados alterados nos testes de...
Pedro, Amélia; Pacheco, Amália; Sousa, Rita; Mendinhos, Gustavo; Miranda, Mariana; Urzal, Cecília; Monteiro, Virgínia; Fraga, TeresaO cancro do colo do útero (CCU) é globalmente um dos tipos de cancro mais comum em mulheres. O rastreio do CCU é indispensável para a deteção e tratamento de lesões neoplásicas cervicais que possam evoluir para neoplasia, com o objectivo de reduzir a incidência deste cancro. Nos últimos anos, têm ocorrido alterações que visam o aumento da eficácia do rastreio. Nomeadamente, o uso de teste de deteção do vírus do...