Introdução: A farmacovigilância consiste da ciência e das atividades relativas à detecção, avaliação, compreensão e prevenção de efeitos adversos ou quaisquer outros possíveis problemas relacionados a medicamentos (OMS, 2005). O Centro de Farmacovigilância do Ceará – CEFACE reúne professores do curso de Farmácia da Universidade Federal do Ceará (UFC), estudantes, entre outros vinculos ao grupo através de projet...
O Centro de Farmacovigilância do Ceará (CEFACE) desenvolveu esse ano um projeto de educação em saúde na Escola Municipal Dom Manuel da Silva Gomes. A extensão do conhecimento em saúde foi somada a prática pedagógica como forma de ampliar o conhecimento dos alunos, considerando a realidade cotidiana desses e respeitando os princípios fundamentais em relação à abordagem de educação a adolescentes. O projeto foi r...
Introdução O serviço de testes alérgicos (STA) baseia-se em atividades relacionadas à farmacovigilância. Segundo a literatura, reações adversas a fármacos são ocorrências comuns na prática diária de Alergia Clínica.O paciente, mediante quadro suspeito de alergia a medicamento, possui várias vertentes de investigação, todas resultando em pesquisas relacionadas a sensibilização a medicamentos, sendo que o aspecto...
Hypersensitivity reactions represent 15% of the universe of adverse drug reactions, among which the most implicated are antibiotics and non-steroidal antiinflammatory drugs (NSAIDs). The objective of the present study was to establish a model an allergic drug testing service (STA) for implantation in public hospitals. It is a descriptive and prospective study. The service was initially implemented at the Dermat...
Objective: The aim of the study was to investigate true β-lactam allergy at a public pediatric hospital. Material and Methods: Children and adolescents with allergy symptoms were referred to the Allergy and Immu-nology Service, Hospital Infantil Albert Sabin, Fortaleza, Brazil. During the allergist interviews, β-lactam drug allergy was suspected in 24 patients. Results: Urticaria, angioedema, erythematous macul...
Drug intoxications are a major public health problem in Brazil. In view of this factor, the present study aimed to carry out a survey on the occurrence of cases of drug intoxication in Brazil in the period from 2013 to 2016. This is a documentary research that fits into the survey modality. With quantitative approach. The data used in the survey were obtained from the National System of Toxic-pharmacological In...
Our aim was to evaluate genetic polymorphism of molecules involved in immunoregulatory/allergic processes in patients who presented with cutaneous hypersensitivity caused by chemically unrelated nonsteroidal anti-inflammatory drugs. Polymorphisms at IL10 (–1082 G>A), IL4 (–589 C>T), CTLA4 (+49A>G), and DAO (+8956 C>G) genes were studied in 55 cases and 97 controls by the polymerase chain reaction-restriction fr...
Drugs are the mainly therapeutical tool to the recoverying or maintenance of the population health condiction. Among the most common problems related for it are Adverse Drug Reactions (ADR) and Technical Complains (TC), being need this survey through the management, and development of activities of pharmacovigillance with the creation of helper’s and notifiers centers. Evaluate the ADR and TC sended to and anal...
BACKGROUND: The morbi-mortality by the use of medicines is a major health problem. The drug adverse reactions may result in death, increased hospitalizations and healthcare costs. OBJECTIVES: Describe and analyze reports of suspected adverse reactions caused by drugs that act on the nervous system (SN-ADR), registered in the database of the Pharmacovigilance Centre of Ceará, from January 1997 to March 2008. MET...