3 documents found, page 1 of 1
Clinical spectrum time course in non-Asian patients positive for anti-MDA5 anti...
Cavagna, Lorenzo; Meloni, Federica; Meyer, Alain; Sambataro, Gianluca; Belliato, Mirko; De Langhe, Ellen; Cavazzana, Ilaria; Pipitone, NicolòObjectives: To define the clinical spectrum time-course and prognosis of non-Asian patients positive for anti-MDA5 antibodies. Methods: We conducted a multicentre, international, retrospective cohort study. Results: 149 anti-MDA5 positive patients (median onset age 53 years, median disease duration 18 months), mainly females (100, 67%), were included. Dermatomyositis (64, 43%) and amyopathic dermatomyositis (47...
Rare clinical manifestations in systemic lupus erythematosus: a review on frequ...
Tani, Chiara; Elefante, Elena; Arnaud, Laurent; Barreira, Sofia; Bulina, Inita; Cavagna, Lorenzo; Costedoat-Chalumeau, Nathalie; Doria, AndreaObjectives: The purpose of this study was to review the frequency and clinical presentation of the rarest clinical manifestations of systemic lupus erythematosus (SLE). Methods: A list of 6 rare SLE manifestations were defined: gastrointestinal, liver, pulmonary, cardiac, ocular and neurological manifestations. Each topic was assigned to a pair of authors to perform a literature search and article review. Resul...
Undifferentiated connective tissue disease : state of the art on clinical pract...
Antunes, Margarida; Scirè, Carlo Alberto; Talarico, Rosaria; Alexander, Tobias; Avcin, Tadej; Belocchi, Chiara; Doria, Andrea; Franceschini, FrancoThe term 'undifferentiated connective tissue disease' (UCTD) is generally used to describe clinical entities characterised by clinical and serological manifestations of systemic autoimmune diseases but not fulfilling the criteria for defined connective tissue diseases (CTDs). In this narrative review, we summarise the results of a systematic literature research, which was performed as part of the ERN ReCONNET p...