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Neutrophil extracellular traps (NETs) exacerbate severity of infant sepsis

Colón, David F.; Wanderley, Carlos W.; Franchin, Marcelo; Silva, Camila M.; Hiroki, Carlos H.; Castanheira, Fernanda V. S.; Donate, Paula B.

Background: Neutrophil extracellular traps (NETs) are innate defense mechanisms that are also implicated in the pathogenesis of organ dysfunction. However, the role of NETs in pediatric sepsis is unknown. Methods: Infant (2 weeks old) and adult (6 weeks old) mice were submitted to sepsis by intraperitoneal (i.p.) injection of bacteria suspension or lipopolysaccharide (LPS). Neutrophil infiltration, bacteremia, ...

Date: 2019   |   Origin: Oasisbr

Exploration of avocado by-products as natural sources of bioactive compounds

Tremocoldi, Maria Augusta; Rosalen, Pedro Luiz; Franchin, Marcelo; Massarioli, Adna Prado; Denny, Carina; Daiuto, Erica Regina [UNESP]

Made available in DSpace on 2018-11-26T15:47:27Z (GMT). No. of bitstreams: 0 Previous issue date: 2018-02-14; Fundacao do Amparo a Pesquisa do Estado de Sao Paulo; This study aimed to evaluate the antioxidant, anti-inflammatory, and cytotoxic properties and phenolic composition of peel and seed of avocado varieties Hass and Fuerte using green solvents. Ethanol soluble compounds were identified in peel and seed ...

Date: 2018   |   Origin: Oasisbr

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