7 documents found, page 1 of 1
Strategy games to improve environmental policymaking
Garcia, C.A.; Savilaakso, S.; Verburg, R.W; Stoudmann, N.; Fernbach, P.; Sloman, S.A.; Peterson, G.D.; Araújo, M.B.; Bastin, J-F.; Boutinot, L.While the scientific community documents environmental degradation and develops scenarios to identify the operational margins of system Earth, less attention is given to how decisions are made that steer the system in one direction or the other. We propose to use strategy games for this purpose, increasing the representation of human agency in scenario development and creating spaces for deliberation between di...
Study of Mob1 in the apicomplexan Toxoplasma gondii: at the crossroads of asexu...
Delgado, I. L.; Francisco, S.; Zúquete, S.; Leitão, A.; Soares, Helena; Nolasco, SofiaToxoplasma gondii, the causative agent of toxoplasmosis, is the uttermost member of apicomplexan parasites due to its zoonotic character. To achieve a sustainable infection, parasites must avoid overgrowth given that uncontrolled parasite growth may lead to the death of both the host and the parasite. Indeed, understanding how parasites regulate their replication rate, namely balancing proliferation versus cell...
Characterization of the Tubulin-binding cofactor B in Toxoplasma gondii, a zoon...
Delgado, I.; Francisco, S.; Santos, D.; Zúquete, S.; Leitão, A.; Soares, Helena; Nolasco, SofiaTubulin cofactors participate in the folding, dimerization, and dissociation pathways of the tubulin dimer, being implicated in the control of tubulin proteostasis and consequently in the control of microtubule (MT) dynamics in vivo. We identified a gene coding for a Tubulin cofactor B in the T. gondii genome and characterized its protein (tgTBCB) in the tachyzoite stage.
Estudo do interactoma da proteína MOB1 de Toxoplasma gondii usando ferramentas ...
Delgado, I. L.; Tavares, A.; Francisco, S.; Santos, D.; Zúquete, S.; Leitão, A.; Soares, Helena; Nolasco, SofiaO protozoário Toxoplasma gondii é um parasita intracelular obrigatório pertencente ao filo Apicomplexa, único pela sua capacidade de infetar qualquer vertebrado. As cinases MOB integram o módulo nuclear da Hippo (humano) e da mitotic exit network (levedura), vias sinalizadoras reguladoras de citocinese, proliferação celular e apoptose, em eucariotas. Através de BLAST, identificámos uma proteína MOB1 em T. gondi...
Student bystander behavior and cultural issues in cyberbullying: when actions s...
Costa Ferreira, P. A. N.; Veiga Simão, A. M.; Ferreira, A.; Souza, S.; Francisco, S.This study aims to investigate whether student bystander interventions can influence the relationship between being a bystander of a cyberbullying incident and being the victim or the aggressor. Another aim is to understand the specific behavior presented by students bystanders, namely whether they noticed incidents of cyberbullying and interpreted these events as an emergency and which actions they determined ...
The two apicomplexa Besnoitia besnoiti and Toxoplasma gondii fifferentially aft...
Cardoso, R.; Francisco, S.; Delgado, Inês; Nolasco, Sofia; Leitão, Alexandra; Soares, HelenaObligate intracellular parasites have co-evolved with hosts to be able to invade their cells and flourish. To be successful they need to establish specific molecular parasite-host cell interactions and then manipulate the host cell structures, mechanisms and pathways in order to replicate and grow. In previous work, we described that upon interaction with the host cell, the apicomplexan Besnoitia besnoiti under...
Tide and wind control of megalopal supply to estuarine crab populations on the ...
Queiroga, Henrique; Almeida, M. J.; Alpuim, T.; Flores, A. A. V.; Francisco, S.; Gonzalez-Gordillo, I.; Miranda, A. I.; Silva, I.; Paula, J.Physical processes that force transport of planktonic larvae of invertebrates are responsible for some of the spatial and temporal variability in recruitment. We investigated the influence of tide- and wind-driven circulation on intra-year variability of megalopal supply to populations of the crab Carcinus maenas in 2 estuaries on the Portuguese west coast. Daily data on physical variables and on supply and set...