14 documents found, page 1 of 2
Evaluation of different diagnostic methods of American Cutaneous Leishmaniasis ...
Espir, Thaís Tibery; Guerreiro, Thayanne Sá; Naiff, Maricleide de Farias; Figueira, Luanda de Paula; Soares, Fabiane Veloso; Silva, Susi Simas daEpidemiological studies have been conducted to better understand the dynamics of American Cutaneous Leishmaniasis (ACL) in the Amazon region where distinct species of Leishmania circulate. In endemic areas, the optimal diagnosis must be made in the earlier clinical presentation to avoid the complications of chronic disease. The scarcity of financial support, laboratory infrastructure and trained persons are the...
Characterization of Endotrypanum Parasites Using Specific Monoclonal Antibodies
Franco, A. M.; MacHado, Gérzia Maria de Carvalho; Naiff, Roberto Daibes; Moreira, Celia F.S.; McMahon-Pratt, Diane; Grimaldi Júnior, Gabriel F.A large number of Endotrypanum stocks (representing an heterogeneous population of strains) have been screened against a panel of monoclonal antibodies (MAbs) derived for selected species of Endotrypanum or Leishmania, to see whether this approach could be used to group/differentiate further among these parasites. Using different immunological assay systems, MAbs considered specific for the genus Endotrypanum (...
The Role of Inflammatory, Anti-Inflammatory, and Regulatory Cytokines in Patien...
Espir, Thaís Tibery; Figueira, Luanda de Paula; Naiff, Maricleide de Farias; Costa, Allyson Guimarães da; Ramalho-Ortigão, Marcelo; Malheiro, AdrianaThe authors discuss in this paper the role of inflammatory, anti-inflammatory, and regulatory cytokines in patients infected with different species of Leishmania in Amazonas State, Brazil. A comparative analysis was made of serum concentrations of these cytokines in the peripheral blood of 33 patients infected with cutaneous leishmaniasis. The isolates were identified as Leishmania guyanensis, L. naiffi, and L....
Topical treatment of experimental cutaneous leishmaniasis in golden hamster (Me...
Comandolli-Wyrepkowski, Claudia Dantas; Grafova, Iryna; Naiff, Maricleide de Farias; Avella, Maurizio; Gentile, Gennaro; Grafov, Andrèi AndriyCurrent treatment of cutaneous leishmaniasis (CL) relies mainly on pentavalent antimonials salts and second-line drugs include pentamidine and amphotericin B, but these therapies have side effects and require parenteral administration. The aim of this work was to evaluate the topical formulations containing pentamidine isethionate (PI) in the experimental treatment of cutaneous leishmaniasis (CL). Golden hamste...
Diversity and abundance of phlebotomine of the genus Lutzomyia (Diptera: Psycho...
Silva, Dílvia F.; Freitas, Rui Alves de; Franco, A. M.The genus Lutzomyia has great importance in the New World, with some species implicated in the transmission of causal agents of leishmaniases, bartonellosis and arboviruses. From April 2003 to June 2004 an investigation was undertaken on the richness and abundance of the sand fly fauna in the northeast area of Manacapuru county, Amazonas State. The captures were carried out, with 16 light traps CDC, in areas of...
First record of Lutzomyia (Trichopygomyia) conviti Ramirez Perez, Martins & Ram...
Pinheiro, Francimeire Gomes; Freitas, Rui Alves de; Rocha, Liliane Coelho da; Franco, A. M.The presence of Lutzomyia conviti Ramirez Perez, Martins & Ramirez, previously found only in Venezuela and Colombia, is recorded for the first time in Brazil. Lutzomyia conviti is now added to the 229 species of Lutzomyia already registered in Brazil and to the 44 identified in São Gabriel da Cachoeira, Amazonas state. Both sexes of L. conviti were collected in 2007 and 2008 with CDC light traps in an environme...
First report of Lutzomyia araracuarensis (Morales & Minter) (Diptera: Psychodid...
Silva, Dílvia F. da; Freitas, Rui Alves de; Franco, A. M.A male of Lutzomyia araracuarensis (Morales & Minter) and possibly six females of this same species were found in the northeastern area of Manacapuru county, Amazonas State. Samples were collected using light traps CDC, from April 2003 to June 2004.
Diversity and distribution of sandflies (Diptera: Psychodidae: Phlebotominae) i...
Gomes, Luis Henrique Monteiro; Albuquerque, Maria Ivonei Carvalho; Rocha, Liliane Coelho da; Pinheiro, Francimeire Gomes; Franco, A. M.This study reports the distribution, ecotopes and fauna diversity of sandflies captured in five training bases on a military reserve in Manaus, state of Amazonas (AM). A total of 10,762 specimens were collected, which were distributed among 58 species, with the highest number recorded at Base Instruction 1 (BI1). A higher rate of species richness was found at the Base Instruction Boina Rajada and low levels of ...
Isoenzymatic characterization of human isolates of Leishmania sp (Kinetoplastid...
Figueira, Luanda de Paula; Zanotti, Michele; Pinheiro, Francimeire Gomes; Franco, A. M.Twenty-three isolates of Leishmania sp from patients in the municipalities of Rio Preto da Eva and Manaus were characterized and identified by means of isoenzyme electrophoresis and the degree of similarity between the organisms was analyzed. The results indicated that Leishmania guyanensis and Leishmania naiffi were present in these two environments and that the Leishmania naiffi samples were heterogenous.
Phlebotomine sand flies (Diptera: Psychodidae: Phlebotominae) in urban rainfore...
Rocha, Liliane Coelho da; Freitas, Rui Alves de; Franco, A. M.The non-flooded upland rainforest fragment in the Federal University of Amazonas Campus is considered one of the world's largest urban tropical woodland areas and Brazil's second largest one in an urban setting. It is located in the city of Manaus, State of Amazonas at 03° 04' 34' S, 59° 57' 30' W, in an area covering nearly 800 hectares. Forty-one (41) sand fly species belonging to genus Lutzomyia were found a...