21 documents found, page 1 of 3
A survey of the European Reference Network EpiCARE on clinical practice for sel...
Baumgartner, Tobias; Carreño, Mar; Rocamora, Rodrigo; Bisulli, Francesca; Boni, Antonella; Brázdil, Milan; Horak, Ondrej; Craiu, Dana; Pereira, CristinaObjective: Clinical care of rare and complex epilepsies is challenging, because evidence-based treatment guidelines are scarce, the experience of many physicians is limited, and interdisciplinary treatment of comorbidities is required. The pathomechanisms of rare epilepsies are, however, increasingly understood, which potentially fosters novel targeted therapies. The objectives of our survey were to obtain an o...
Long-term safety and efficacy of patisiran for hereditary transthyretin-mediate...
Adams, David; Polydefkis, Michael; González-Duarte, Alejandra; Wixner, Jonas; Kristen, Arnt V.; Schmidt, Hartmut H.; Berk, John L.Background: Hereditary transthyretin-mediated amyloidosis is a rare, inherited, progressive disease caused by mutations in the transthyretin (TTR) gene. We assessed the safety and efficacy of long-term treatment with patisiran, an RNA interference therapeutic that inhibits TTR production, in patients with hereditary transthyretin-mediated amyloidosis with polyneuropathy. Methods: This multicentre, open-label ex...
Sensory marketing at the destination level: a conceptual approach
Correia, Ricardo; Franco, Ana; Meneses, RaquelMarketing strategies adopted in many destinations do not take into consideration the potential of the senses to generate memorable experiences. By ignoring a driving force of intangibility, such strategies do not value a major source of differentiation. In fact, in a time where the intangible assumes an essential role, the senses emerge as a key for the differentiation of a particular destination when compared ...
Os 5 sentidos associados a Portugal na perspectiva dos turistas
Franco, Ana; Correia, Ricardo; Meneses, RaquelConsiderando a importância dos cinco sentidos para o marketing turístico, procurou-se conhecer as sensações experienciadas e recordadas pelos turistas estrangeiros que visitam Portugal de forma a responder às seguintes questões: Como é que os turistas de diversos países experienciam Portugal? Como é caraterizado Portugal a nível sensorial pelos turistas? Quais os sentidos a enfatizar nas estratégias ...
How to teach fully illiterate adults to read.
Kolinsky, Régine; Carvalho, Cristina; Leite, Isabel; Franco, Ana; Morais, JoséAbout 750 million adults (15%) worldwide lack any literacy skills, most because they lack adequate learning opportunities (UNESCO, 2016). In this chapter, we discuss how to teach to read to such people. We first examine scientific evidence suggesting that literacy acquisition does not radically differ as a function of age of acquisition. We then discuss the data relevant for designing effective methods aimed at...
Relatório de Estágio Curricular – Centro Hospitalar Cova da Beira (Covilhã)
Franco, AnaO presente relatório tem como objetivo descrever as tarefas realizadas durante o estágio curricular, no Centro Hospitalar Cova da Beira, localizado na Covilhã. O Centro Hospitalar Cova da Beira é uma entidade pública empresarial (E.P.E) que tem como finalidade prestar serviços de saúde à comunidade em que está inserida, contando atualmente com 1335 colaboradores. O estágio teve a duração de 400 horas e as ativi...
Completely illiterate adults can learn to read in less than three months
Kolinsky, Régine; Leite, Isabel; Carvalho, Crsitina; Franco, Ana; Morais, JoséThe purpose of this case series was to explore whether adults who did not have the opportunity to acquire reading skills during childhood are able to do so rapidly if trained with an adequate literacy program. After 14 weeks of training with a new, optimized, literacy course based on cognitive research, six out of eight participants became able to read words they had never encountered, hence demonstrating that ...
From illiteracy to literacy in adult- hood: A microlongitudinal study
Kolinsky, Régine; Franco, Ana; Leite, Isabel; Carvalho, Cristina; Fernandes, Tânia; Calcus, Axelle; Morais, JoséLittle is known about literacy acquisition in adults. Yet, our former studies suggest that the majority of the changes induced by literacy in children also occur in adulthood. Based on this observation as well as on what we know from developmental studies on reading acquisition, we designed an intensive literacy course in which each difficulty (either phono- logical or visual) of the alphabetic code is introduc...
Face and object visual processing linked to literacy: a longitudinal study
Franco, Ana; Leite, Isabel; Carvalho, Cristina; deGelder, Beatrice; Morais, José; Kolinsky, RégineReading is a cultural invention too recent to involve dedicated genetic or developmental mechanisms. It has been proposed that reading partly recycles pre-existing brain systems (neural recycling hypothesis, Dehaene, 2004). This hypothesis is supported by fMRI studies. Reading acquisition does not only lead to the development of a strong response to written materials in the left fusiform gyrus, the "visual word...
Caracterização da prática dos técnicos de radiologia em tomossíntese mamária em...
Franco, Ana; Boavida, Filipa; Dias, Verónica; Reis, CláudiaEm Portugal, mamógrafos com tomossíntese integrada têm sido implementados ainda que não existam protocolos definidos globalmente. Este estudo pretende averiguar qual o tipo de formação disponibilizada aos técnicos de radiologia (TR) nesta técnica de imagem e caracterizar as práticas em tomossíntese mamária (TM) em instituições da região de Lisboa.