8 documents found, page 1 of 1
Swine and poultry pathogens: The complete genome sequences of two strains of My...
Vasconcelos, Ana Tereza; Ferreira, Henrique Bunselmeyer; Bizarro, Cristiano Valim; Bonatto, Sandro L.; Carvalho, Marcos O.; Pinto, Paulo MarcosThis work reports the results of analyses of three complete mycoplasma genomes, a pathogenic (7448) and a nonpathogenic (J) strain of the swine pathogen Mycoplasma hyopneumoniae and a strain of the avian pathogen Mycoplasma synoviae; the genome sizes of the three strains were 920,079 bp, 897,405 bp, and 799,476 bp, respectively. These genomes were compared with other sequenced mycoplasma genomes reported in the...
The complete genome sequence of Chromobacterium violaceum reveals remarkable an...
Vasconcelos, Ana Tereza; De-Almeida, Darcy Fontoura; Hungría, Mariangela; Guimarães, Cláudia Teixeira; Antônio, Regina VasconcellosChromobacterium violaceum is one of millions of species of free-living microorganisms that populate the soil and water in the extant areas of tropical biodiversity around the world. Its complete genome sequence reveals (i) extensive alternative pathways for energy generation, (ii) ≈500 ORFs for transport-related proteins, (iii) complex and extensive systems for stress adaptation and motility, and (iv) wide-spre...
Structural and evolutionary insights into endogenous alpha-phospholipase A2 inh...
Estevão-Costa, Maria Inácia; Fernandes, Carlos Alexandre H. [UNESP]; Mudadu, Maurício De Alvarenga; Franco, Glória ReginaMade available in DSpace on 2018-12-11T16:40:58Z (GMT). No. of bitstreams: 0 Previous issue date: 2016-03-15; Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq); Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP); Phospholipases A2 are major components of snake venoms (svPLA2s) and are able to induce multiple local and systemic deleterious effects upon envenomation. Several snake sp...
The polymorphism rs17782313 near MC4R gene is related with anthropometric chang...
Resende, Cristina Maria Mendes; Durso, Danielle Fernandes; Borges, Karina Braga Gomes; Pereira, Rafaela Messias; Rodrigues, Gisele Kuhlmann DuarteObjective: Evaluate whether the polymorphism rs17782313 near MC4R gene influences long-term outcomes after bariatric surgery. Methods: The rs16782313 polymorphism was genotyped in 217 individuals undergoing bariatric surgery and analyzed in detail in 141 women. Data for comorbidities, BMI, excess weight loss (EWL), and body composition were obtained before and during 60 months after surgery. Results: The risk a...
Effect of ionizing radiation exposure on Trypanosoma cruzi ubiquitin-proteasome...
Cerqueira, Paula Gonçalves; Silva, Danielle Gomes Passos; Rocha, João Pedro Vieira da; Mendes, Isabela Cecilia; Oliveira, Karla Andrade detIn recent years, proteasome involvement in the damage response induced by ionizing radiation (IR)became evident. However, whether proteasome plays a direct or indirect role in IR-induced damageresponse still unclear. Trypanosoma cruzi is a human parasite capable of remarkable high tolerance toIR, suggesting a highly efficient damage response system. Here, we investigate the role of T. cruzi pro-teasome in the ...
Genetic profiling of Trypanosoma cruzi directly in infected tissues using neste...
Pimenta, Juliana Ramos; Freitas, Jorge Marcelo de; Duffy, Tomás; Bartholomeu, Daniella Castanheira; Oliveira, Riva de Paula; Chiari, EglerThe investigation of the importance of the genetics of Trypanosoma cruzi in determining the clinical course of Chagas disease will depend on precise characterisation of the parasites present in the tissue lesions. This can be adequately accomplished by the use of hypervariable nuclear markers such as microsatellites. However the unilocal nature of these loci and the scarcity of parasites in chronic lesions make...
Unequivocal identification of subpopulations in putative multiclonal Trypanosom...
Valadares, Helder Magno Silva; Pimenta, Juliana Ramos; Segatto, Marcela; Veloso, Vanja Maria; Gomes, Mônica Lúcia; Chiari, Egler; Gollob, Kenneth JohnTrypanosoma cruzi, the etiological agent of Chagas disease, is a polymorphic species. Evidence suggests that the majority of the T. cruzi populations isolated from afflicted humans, reservoir animals, or vectors are multiclonal. However, the extent and the complexity of multiclonality remain to be established, since aneuploidy cannot be excluded and current conventional cloning methods cannot identify all the r...
Molecular studies of the brazilian infectious bronchitis virus isolates
Abreu, Josiane Tavares de; Mourão, Marina de Moraes; Santos, Carlos Eduardo Fernandes dos; Veloso, Caio Júlio Martins; Resende, José Sérgio deSubmitted by Regina Mello (mrmello@inmetro.gov.br) on 2011-02-09T13:16:42Z No. of bitstreams: 1 2010_AbreuMourãoSantos.pdf: 74538 bytes, checksum: 13351d05f4f85b5d2d584d171b8cc0f4 (MD5); Approved for entry into archive by Claudia Araujo(caraujo@inmetro.gov.br) on 2011-02-28T16:15:59Z (GMT) No. of bitstreams: 1 2010_AbreuMourãoSantos.pdf: 74538 bytes, checksum: 13351d05f4f85b5d2d584d171b8cc0f4 (MD5); Made availa...