11 documents found, page 1 of 2
Bacterial nanocellulose membrane as novel substrate for biomimetic structural c...
Suleimenova, Akmaral; Frasco, Manuela F.; Soares da Silva, Francisco A.G.; Gama, Miguel; Fortunato, Elvira; Sales, M. Goreti F.The development of optical biosensors based on structural colors generated by short-range ordered colloidal particles is attracting growing interest due to their non-iridescent and non-fading features. In this study, a biomimetic approach using biopolymers for the various steps of sensor construction is presented. Bacterial nanocellulose (BNC) has many foreseen applications in biomedical engineering because of ...
Detection of serum calprotectin based on molecularly imprinted photonic hydroge...
Resende, Sara; Frasco, Manuela F.; Freitas, Paulo P.; Sales, M. Goreti F.Inflammatory bowel disease (IBD) affects millions of people worldwide, and current diagnosis relies on a number of complex procedures. The need for sensitive diagnostic tools has focused research on discovering new biomarkers and improving detection methods. Serum calprotectin has recently emerged as a new serological biomarker and shows great potential due to its high specificity. In this work, a label-free bi...
Breaking the classics: Next-generation biosensors for the isolation, profiling ...
Vaz, Raquel; Serrano, Verónica M.; Castaño-Guerrero, Yuselis; Cardoso, Ana R.; Frasco, Manuela F.; Sales, M. Goreti F.Extracellular vesicles (EVs) contain biomarkers that may represent a paradigm shift in timely disease diagnosis and personalized therapeutic approaches. Despite tremendous progress in this field, the considerable complexity and heterogeneity of EVs, combined with hurdles in isolation and accurate characterization, have delayed their envisioned clinical translation. At the same time, emerging biosensor technolog...
Recent advances in virus imprinted polymers
Amorim, Mariana S.; Sales, M.Goreti F.; Frasco, Manuela F.Molecular imprinting is a mature and appealing technology to obtain highly selective recognition sites created within a polymeric network, having other important features such as robustness and cost effectiveness. The applications of molecularly imprinted polymers (MIPs) are vast, but there is a continuous particular interest in their integration into sensing devices. MIPs possess remarkable properties in terms...
Emerging Optical Materials in Sensing and Discovery of Bioactive Compounds
Vaz, Raquel; Valpradinhos, Beatriz; Frasco, Manuela F.; Sales, Maria Goreti F.Optical biosensors are used in numerous applications and analytical fields. Advances in these sensor platforms offer high sensitivity, selectivity, miniaturization, and real-time analysis, among many other advantages. Research into bioactive natural products serves both to protect against potentially dangerous toxic compounds and to promote pharmacological innovation in drug discovery, as these compounds have u...
Biosensors for European Zoonotic Agents: A Current Portuguese Perspective
Miguéis, Samuel da Costa; Tavares, Ana P. M.; Martins, Gabriela V.; Frasco, Manuela F.; Sales, Maria Goreti FerreiraEmerging and recurrent outbreaks caused by zoonotic agents pose a public health risk. They result in morbidity and mortality in humans and significant losses in the livestock and food industries. This highlights the need for rapid surveillance methods. Despite the high reliability of conventional pathogen detection methods, they have high detection limits and are time-consuming and not suitable for on-site anal...
Molecular Imprinting on Nanozymes for Sensing Applications
Cardoso, Ana R.; Frasco, Manuela F.; Serrano, Verónica M.; Fortunato, Elvira; Sales, Maria Goreti FerreiraAs part of the biomimetic enzyme field, nanomaterial-based artificial enzymes, or nanozymes, have been recognized as highly stable and low-cost alternatives to their natural counterparts. The discovery of enzyme-like activities in nanomaterials triggered a broad range of designs with various composition, size, and shape. An overview of the properties of nanozymes is given, including some examples of enzyme mimi...
Molecular Imprinting on Nanozymes for Sensing Applications
Cardoso, Ana Rita; Frasco, Manuela F.; Serrano, Verónica; Fortunato, Elvira; Sales, Maria Goreti FerreiraAs part of the biomimetic enzyme field, nanomaterial-based artificial enzymes, or nanozymes, have been recognized as highly stable and low-cost alternatives to their natural counterparts. The discovery of enzyme-like activities in nanomaterials triggered a broad range of designs with various composition, size, and shape. An overview of the properties of nanozymes is given, including some examples of enzyme mimi...
Photonics in nature and bioinspired designs: sustainable approaches for a colou...
Vaz, Raquel; Frasco, Manuela F.; Sales, M. Goreti F.Biological systems possess nanoarchitectures that have evolved for specific purposes and whose ability to modulate the flow of light creates an extraordinary diversity of natural photonic structures. In particular, the striking beauty of the structural colouration observed in nature has inspired technological innovation in many fields. Intense research has been devoted to mimicking the unique vivid colours with...
Photonics in nature and bioinspired designs: sustainable approaches for a colou...
Vaz, Raquel; Frasco, Manuela F.; Sales, M. Goreti F.Biological systems possess nanoarchitectures that have evolved for specific purposes and whose ability to modulate the flow of light creates an extraordinary diversity of natural photonic structures. In particular, the striking beauty of the structural colouration observed in nature has inspired technological innovation in many fields. Intense research has been devoted to mimicking the unique vivid colours with...