5 documents found, page 1 of 1
Sensitivity and specificity of the circulating cathodic antigen rapid urine tes...
Fernanda Teixeira Ferreira; Thiago André Fidelis; Thiago Almeida Pereira; Alba Otoni; Leonardo Campos Queiroz; Frederico Figueiredo AmâncioINTRODUCTION: The Kato-Katz technique is the standard diagnostic test for Schistosoma mansoni infection in rural areas. However, the utility of this method is severely limited by the day-to-day variability in host egg excretion in the stool. In high-transmission areas, the point-of-care circulating cathodic antigen (POC-CCA) urine assay has proven to be a reliable test. However, investigations of the reliabilit...
Aumento da carga de dengue no Brasil e unidades federadas, 2000 e 2015: análise...
Valdelaine Etelvina Miranda Dearaújo; Juliana Maria Trindade Bezerra; Frederico Figueiredo Amâncio; Valéria Maria de Azeredo Passos; Mariângela CarneiroObjetivo: Descrever as principais métricas sobre dengue geradas pelo Global Burden of Disease (GBD) Study 2015, para o Brasil e suas 27 unidades federadas, nos anos de 2000 e 2015. Métodos: As métricas descritas foram: taxas de incidência e de mortalidade por dengue, padronizadas por idade, years of life lost (YLL), years lived with disability (YLD) e disability adjusted life years (DALY) (frequência absoluta e...
Thrombocytopenia as a marker of liver steatosis in a low-endemic area for schis...
Albaotoni; Carlos Mauricio de Figueiredo Antunes; Fernanda Ferreira Tavares; Débora Heloísa Quadros Araújo; Thiago de Almeida PereiraIntroduction: Thrombocytopenia is commonly found in patients living in highly endemic areas for Schistosoma mansoni. Recently, different degrees of liver steatosis have also been associated with low platelet counts worldwide. We investigated the association of platelet counts with hepatosplenic schistosomiasis and with liver steatosis in an area of low prevalence of schistosomiasis in Brazil. Method: Pains, a c...
Osteopontin is upregulated in human and murine acute schistosomiasis mansoni
Thiago Almeidapereira; Rafal p Witek; William Evan Secor; Fausto Edmundo Lima Pereira; Jose Roberto Lambertucci; Anna Mae Diehl; Wing-kin SynBackground Symptomatic acute schistosomiasis mansoni is a systemic hypersensitivity reaction against the migrating schistosomula and mature eggs after a primary infection. The mechanisms involved in the pathogenesis of acute schistosomiasis are not fully elucidated. Osteopontin has been implicated in granulomatous reactions and in acute hepatic injury. Our aims were to evaluate if osteopontin plays a role in ac...
Emergence of chikungunya and zika in a municipality endemic to dengue, Santa Lu...
Farley Liliana Romero Braga; Juliana Maria Trindade Bezerra; Rodrigo Fabiano de Carmo Said; Aloysio Nogueira da Gama Neto; Emanuela Cardoso CotrimIntroduction: The recent circulation of arboviruses transmitted by vectors, such as dengue, chikungunya, and Zika, is concerning due to the high morbidity rates, clinical complications, and increased demand on health services. The objective of this study was to analyze the clinical and epidemiological aspects of an epidemic caused by arboviruses in the municipality of Santa Luzia, Minas Gerais, Brazil. Methods:...