2 documents found, page 1 of 1
Mo-CBP3, an antifungal Chitin-Binding Protein from Moringa oleifera Seeds, is a...
Freire, José E. C.; Vasconcelos, Ilka M.; Moreno, Frederico B. M. B.; Batista, Adelina B.; Lobo, Marina D. P.; Pereira, Mirella L.; Lima, João P. M. S.Mo-CBP3 is a chitin-binding protein from M. oleifera seeds that inhibits the germination and mycelial growth of phytopathogenic fungi. This protein is highly thermostable and resistant to pH changes, and therefore may be useful in the development of new antifungal drugs. However, the relationship of MoCBP3 with the known families of carbohydrate-binding domains has not been established. In the present study, fu...
A chitin-binding protein purified from Moringa oleifera seeds presents anticand...
S. Neto, João X.; Pereira, Mirella L.; Oliveira, Jose T. A.; Bezerra, Lady C. B. Rocha; Lopes, Tiago D. P.; Costa, Helen P. S.; Sousa, Daniele O. B.Candida species are opportunistic pathogens that infect immunocompromised and/or immunosuppressed patients, particularly in hospital facilities, that besides representing a significant threat to health increase the risk of mortality. Apart from echinocandins and triazoles, which are well tolerated, most of the antifungal drugs used for candidiasis treatment can cause side effects and lead to the development of ...