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Synergistic effect of the L-tryptophan and kynurenic acid with dipyrone or para...
Rocha, Nayrton Flávio Moura; Rios, Emiliano Ricardo Vasconcelos; Carvalho, Alyne Mara Rodrigues; Freire, Leonardo Vasconcelos; Dias, Marília LeitePurpose: Our great interest in this work was study the synergism between L-tryptophan and dipyrone or paracetamol as well as the interaction of kynurenic acid (L-tryptophan metabolite) and these analgesics agents utilizing a robust methodology. Methods: We performed the writhing test induced by acetic acid in mice to evaluate the antinociceptive effect of the treatments isolated and combined (p.o. and i.p.). Do...
Data: 2014
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Origem: Oasisbr