Due to the long asymptomatic phase and lack of effective early-stage diagnosis, lung cancer is one of the deadliest types of cancer worldwide. To expedite disease diagnosis, the quantification of target biomarkers in human serum is a propitious approach. However, the low concentrations of biomarkers in human serum and their tendency to be masked by abundant proteins [immunoglobulin G (IgG) and human serum album...
Introduction. Obstructive sleep apnoea syndrome (OSAS) is frequently associated to other morbid conditions that act as risk factors influencing OSAS morbidity and mortality. Aim. To analyse the presence of co-morbidities in OSAS patients, recruited from a sleep outpatient clinic in Northern Portugal, stratified as a function of OSAS severity. Patients and methods. A cohort of 319 sleep-disordered patients was a...