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Multi-target analysis of cytostatics in hospital effluents over a 9-month period

Gouveia, T.I.A; Silva, A.M.T; Freire, M.G.; Sousa, A.C.; Alves, A.; Santos, M.S.F.

The consumption of cytostatics, pharmaceuticals prescribed in chemotherapy, is increasing every year and worldwide, along with the incidence of cancer. The presence and the temporal evolution of cytostatics in wastewaters from a Portuguese hospital center was evaluated through a 9-month sampling campaign, comprising a total of one hundred and twenty-nine samples, collected from May 2019 to February 2020. Eleven...


Pristine Multi-walled carbon nanotubes for a rapid and efficient plasmid DNA cl...

Ferreira, P.; Riscado, M.; Bernardo, S.; Freire, M.G.; Faria, J.L.; Tavares, A.P.M.; Silva, C.G.; Sousa, F.

Therapeutic approaches based on nucleic acids to modulate cell activity have recently gained attention. These molecules arise from complex biotechnological processes, requiring effective manufacturing strategies, high purity, and precise quality control to be used as biopharmaceuticals. One of the most critical and time-consuming steps for nucleic acids-based biotherapeutics manufacturing is their purification,...


High performance of ionic-liquid-based materials to remove insecticides

Francisco, R.; Almeida, C.; Sousa, Ana Catarina A.; Neves, M.C.; Freire, M.G.

Neonicotinoids are systemic insecticides commonly used for pest control in agriculture and veterinary applications. Due to their widespread use, neonicotinoid insecticides (neonics) are found in different environmental compartments, including water, soils, and biota, in which their high toxicity towards non-target organisms is a matter of great concern. Given their widespread use and high toxicity, the developm...


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