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Identification of the MYST3-CREBBP fusion gene in infants with acute myeloid le...

Andrade,Francianne Gomes; Noronha,Elda Pereira; Baseggio,Rosania Maria; Fonseca,Teresa Cristina Cardoso; Freire,Bruno Marcelo Rocha

ABSTRACT Background: Acute myeloid leukemia presenting the MYST3-CREBBP fusion gene is a rare subgroup associated with hemophagocytosis in early infancy and monocytic differentiation. The aim of this study was to define the relevant molecular cytogenetic characteristics of a unique series of early infancy acute myeloid leukemia cases (≤24 months old), based on the presence of hemophagocytosis by blast cells at ...

Date: 2016   |   Origin: Oasisbr
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