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Dairying, diseases and the evolution of lactase persistence in Europe

Evershed, Richard P.; Davey Smith, George; Roffet-Salque, Mélanie; Timpson, Adrian; Diekmann, Yoan; Lyon, Matthew S.; Cramp, Lucy J. E.

In European and many African, Middle Eastern and southern Asian populations, lactase persistence (LP) is the most strongly selected monogenic trait to have evolved over the past 10,000 years(1). Although the selection of LP and the consumption of prehistoric milk must be linked, considerable uncertainty remains concerning their spatiotemporal configuration and specific interactions(2,3). Here we provide detaile...


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