7 documents found, page 1 of 1
Protective Effect of cashew gum (Anacardium occidentale L.) on 5-Fluorouracil-i...
Miranda, João Antônio Leal de; Barreto, João Erivan Façanha; Martins, Dainesy Santos; Pimentel, Paulo Vitor de Souza; Costa, Deiziane Viana da SilvaIntestinal mucositis is a common complication associated with 5-fluorouracil (5-FU), a chemotherapeutic agent used for cancer treatment. Cashew gum (CG) has been reported as a potent anti-inflammatory agent. In the present study, we aimed to evaluate the e ect of CG extracted from the exudate of Anacardium occidentale L. on experimental intestinal mucositis induced by 5-FU. Swiss mice were randomly divided into...
Efeito de subtrações da proteína do látex da Calotropis procera na mucosite ora...
Freitas, Ana Paula Fragoso deOral mucositis is one of the most common collateral effects in patients undergoing treatment with 5-fluorouracil (5-FU). In this context, It has been previously shown that with only two doses of the protein from the latex fraction of Calotropis procera it was possible to prevent damage caused by 5-FU in the oral mucosa. Thus, the aim of this study was investigate the effect of subfractions of the latex protein ...
Side-effects of irinotecan (CPT-11), the clinically used drug for colon cancer ...
Alencar, Nylane Maria Nunes de; Bitencourt, Flávio da Silveira; Figueiredo, Ingrid Samantha Tavares de; Luz, Patrícia BastosIntestinal mucositis (IM) is the critical side effect of irinotecan (CPT-11), which is the front-line drug used for the treatment of colorectal cancer. This study aimed to evaluate the effectiveness of latex proteins (LP) from Calotropis procera to prevent IM and diarrhea in animals. Swiss mice were treated daily with saline or LP (1, 5, or 50 mg/kg, i.v.) 24 h prior to CTP-11 (75 mg/kg/4 days, i.p) and for add...
Síndrome do Roubo da Subclávia e Síndrome do Roubo coronário-subclávio : um res...
Barbosa, Maria Lucianny Lima; Pereira, Ana Rafaela Silva; Moura, Rosielle Alves de; Costa Sobrinho, Osvaldo Pereira da; Pessoa, Daniela França Barroshe syndrome of coronary-subclavian steal is defined as the reversed blood fl ow in a coronary artery by means of a grafting of the left internal mammary artery tow ard the middle-distal subclavian, and occurs due to severe stenosis or total occlusion of th e proximal portion of the latter. It is a disease with significant morbidity with po ssible complications such as thrombosis, anoxia and death. The objective...
Auto-exame das mamas como fator de prevenção ao câncer: uma abordagem com estud...
Almeida, Michele Santana Pacheco de; Silva, Vânia de Santana; Silva, Itaciara de Oliveira do Carmo da; Esquivel, Deivid Silva de AraújoThis study aimed to evaluate the knowledge that the students of the Youth and Adult Education in High School, a public school in São Francisco do Conde, Bahia, present on concepts and importance of breast examination as a preventive factor for cancer early breast. The research was developed through an exploratory study of descriptive, quantitative type based on an evaluation questionnaire administered to a popu...
Aspectos toxicológicos da Benzidamina
Callou, Iana Bantim Felicio; Siqueira, Rafaelly Maria Pinheiro; Carvalho, Mailson Fontes de; Freitas, Ana Paula Fragoso de; Mariz, Saulo RiosThe drug abuse has been the object of several research. Among these substances, the benzydamine is widely used as an anti-inflammatory and as a drug of abuse. We conducted a literature review about the "toxicological aspects of benzydamine”, focusing on clinical issues, both with regard to therapeutic effects as toxic aspects. A literature review was conducted through the databases Pubmed, Scielo, Lilacs and Me...
Fração protéica do látex da Calotropis procera protege contra a mucosite oral i...
Freitas, Ana Paula Fragoso deMucosite oral (MO) induzida por drogas antineoplásicas é um importante fator limitante da dose e efeitos colaterais da terapia do câncer. Calotropis procera é uma planta que produz látex constitutivamente abundante que é relatado possuir propriedades antiinflamatórias, bactericidas, inseticidas, analgésicas. O presente trabalho teve como objetivo descrever o efeito das proteínas do látex da Calotropis procera (...