Background & Aim: The Human Resources sector is experiencing significant transformation due to ongoing technological advancements. A particularly relevant topic within this evolution is Online Recruitment (OR), a relatively recent approach in Recruitment and Selection (R&S). However, there is a notable lack of literature focused on the perspectives of recruiters in Portugal regarding this method. This s...
Este texto resulta de uma pesquisa em curso que tem como principal objetivo explorar a influência das questões de género, em particular do fenómeno de violência contra as mulheres com comportamentos aditivos e dependências, nas práticas profissionais ao nível dos cuidados de saúde. A análise das políticas públicas e as questões que emergem da reflexão sobre as práticas profissionais sugerem-nos a existência de ...
Melanoma is the deadliest type of skin cancer, with about 61,000 deaths annually worldwide. Late diagnosis increases mortality rates due to melanoma’s capacity to metastasise rapidly and patients’ resistance to the available conventional therapies. Consequently, the interest in natural products as a strategy for drug discovery has been emerging. Propolis, a natural product produced by bees, has several biologic...
Propolis, a natural product made by bees with resins and balsams, is known for its complex chemical composition and remarkable bioactivities. In this study, propolis extraction was studied seeking extracts with strong bioactivities using less orthodox solvents, with some derived from apiary products. For that, a propolis sample collected from Gerês apiary in 2018 (G18) was extracted by maceration with six diffe...
Melanoma is the most aggressive and life-threatening skin cancer type. The melanoma genome is the most frequently mutated, with the <i>BRAF</i> mutation present in 40–60% of melanoma cases. <i>BRAF</i>-mutated melanomas are characterized by a higher aggressiveness and progression. Adjuvant targeted treatments, such as BRAF and MEK inhibitors, are added to surgical excision in <i>BRAF</i>-mutated metastatic mela...
Abstract Aims Assess the antibacterial and antioxidant effects of ethanol extracts of Portuguese propolis samples when combined with gentamicin, a widely used aminoglycoside antibiotic, or with honey, collected from the same apiary as propolis. Methods and Results Using the agar dilution method and DPPH free radical scavenging assay, antimicrobial and antioxidant synergistic effects between propolis and gentami...
Renal cell carcinoma is the most lethal cancer of the urological system due to late diagnosis and treatment resistance. Propolis, a beehive product, is a valuable natural source of compounds with bioactivities and may be a beneficial addition to current anticancer treatments. A Portuguese propolis sample, its fractions (<i>n</i>-hexane, ethyl acetate, <i>n</i>-butanol and water) and three subfractions (<b>P1</b...
Global demand for safe, effective and natural products has been increasing in parallel with consumers’ concerns about personal and environmental health. Propolis, a traditional and potentially medicinal product with several health benefits, is a beehive product with a worldwide reputation. However, despite the bioactivities reported, the low productivity and high chemical heterogeneity have been extensively ham...
Propolis is a complex mixture of resinous and balsamic material collected by bees from various plant sources which is then processed by salivary enzymes and mixed with other substances like beeswax. This natural product has several biological activities that may provide a wide range of applications. However, propolis low productivity and high diversity hamper its full and efficient use. In order to increase pro...