12 documents found, page 1 of 2
Prognostic Accuracy of the Modified CHA2DS2-VASc Score in COVID-19 Patients Adm...
Valente Silva, Beatriz; Plácido, Rui; Jorge, Cláudia; Mendonça, Carlos; Urbano, Maria Luísa; Rodrigues, Tiago; Brito, Joana; Alves da Silva, PedroIntroduction: Risk factors comprising the CHA2DS2VASc score are recognized as risk factors for venous thromboembolism and mortality in COVID-19 patients. A modified CHA2DS2VASc score (M-CHA2D2VASc), developed by changing gender criteria from female to male, has been proposed to predict in-hospital mortality in COVID-19 patients. The aim of this study was to evaluate the prognostic accuracy of M-CHA2D2VASc for a...
The accuracy of Hestia and simplified PESI to predict the prognosis in pulmonar...
Palas, Miguel; Valente Silva, Beatriz; Jorge, Cláudia; Almeida, Ana G.; Pinto, Fausto J.; Caldeira, DanielIntroduction Pulmonary embolism (PE) patients at low risk of early complications may be considered for early discharge or home treatment. Last decades evidence has been growing about the safety of several clinical prediction rules for selecting those patients, such as simplified Pulmonary Embolism Severity Index (sPESI) and Hestia Criteria. The aim of this review was to compare the safety of both strategies reg...
Pulmonary embolism and COVID-19: a comparative analysis of different diagnostic...
Valente Silva, Beatriz; Jorge, Cláudia; Plácido, Rui; Mendonça, Carlos; Urbano, Maria Luísa; Rodrigues, Tiago; Brito, Joana; Alves da Silva, PedroObjective: Pulmonary embolism (PE) is a common complication of SARS-CoV-2 infection. Several diagnostic prediction rules based on pretest probability and D-dimer have been validated in non-COVID patients, but it remains unclear if they can be safely applied in COVID-19 patients. We aimed to compare the diagnostic accuracy of the standard approach based on Wells and Geneva scores combined with a standard D-dimer...
The CTo-aBCDE score : a new predictor of success in chronic total occlusions
Rigueira, Joana; Aguiar-Ricardo, Inês; Menezes, Miguel Nobre; Santos, Rafael; Rodrigues, Tiago; Cunha, Nelson; Francisco, Ana RitaIntroduction: Patient selection for percutaneous coronary intervention (PCI) in chronic total occlusions (CTOs) is crucial to procedural success. Our aim was to identify independent predictors of success in CTO PCI in order to create an accurate score. Methods: In a single-center observational registry of CTO PCI, demographic and clinical data and anatomical characteristics of coronary lesions were recorded. Li...
Intravenous thrombolysis for acute ischemic stroke after recent myocardial infa...
Marto, João Pedro; Azevedo Kauppila, Linda; Jorge, Cláudia; Calado, Sofia; Viana-Baptista, Miguel; Melo, Teresa Pinho e; Fonseca, Ana CatarinaBackground and Purpose- The safety of IV r-tPA (intravenous tissue-type plasminogen activator) for acute ischemic stroke (AIS) treatment after recent myocardial infarction (MI) is still a matter of debate. We studied the safety of delivering IV r-tPA to AIS patients with a MI within the preceding 3 months. Methods- Retrospective review of consecutive AIS admitted to 2 tertiary university hospitals' and systemat...
Comparative analysis of fractional flow reserve and instantaneous wave-free rat...
Menezes, Miguel Nobre; Francisco, Ana Rita G.; Carrilho-Ferreira, Pedro; Jorge, Cláudia; Torres, Diogo; Cardoso, Pedro; Duarte, José AntónioIntroduction and Objective: Assessment of coronary lesions by the instantaneous wave free ratio (iFR) has generated significant debate. We aimed to assess the diagnostic performance of iFR and its impact on the decision to use fractional flow reserve (FFR) and on procedural characteristics. Methods: In this single-center registry of patients undergoing functional assessment of coronary lesions, FFR was used as ...
Balloon aortic valvuloplasty in the transcatheter aortic valve implantation era...
Francisco, Ana Rita G.; Menezes, Miguel Nobre; Carrilho-Ferreira, Pedro; Jorge, Cláudia; Silva, Doroteia; Oliveira, Eduardo Infante de; Pinto, Fausto J.Introduction: Percutaneous balloon aortic valvuloplasty (BAV) has been limited by the risk of complications and restenosis. However, growing use of transcatheter aortic valve implantation (TAVI) has revived interest in this technique. We analyzed the current indications for BAV and outcomes in a single center. Methods: Acute results and long-term outcomes were analyzed in a retrospective single-center registry ...
Efficacy and safety of percutaneous left atrial appendage closure in chronic ki...
Vieira, Miguel Bigotte; Menezes, Miguel Nobre; Francisco, Ana Rita; Jorge, Cláudia; Carrilho-Ferreira, Pedro; Carpinteiro, LuísINTRODUCTION AND AIMS: Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia, the most devastating complication being thromboembolism leading to fatal or disabling stroke. Although oral anticoagulation (OAC) is the mainstay of prevention therapy in the general population, its benefit in chronic kidney disease (CKD) patients is less well defined. End-stage renal disease patients treated with v...
Circulating mir-122-5p/mir-133b ratio is a specific early prognostic biomarker ...
Dias, Nuno Cortez; Costa, Marina C.; Silva, Doroteia; Jorge, Cláudia; Calisto, Carina; Pessoa, Teresa; Martins, Susana Robalo; Sousa, João Carvalho deBackground: MicroRNAs (miRNAs) are key players in cardiovascular development and disease. However, not only miRNAs of a cardiac origin have a critical role in heart function. Recent studies have demonstrated that miR-122-5p, a hepatic miRNA, increases in the bloodstream during ischemic cardiogenic shock and it is upregulated in the infarcted myocardium. The aim of the present study was to determine the potentia...
Coronary fistulas in a patient with a novel long QT syndrome mutation
Plácido, Rui; Dias, Nuno Cortez; Veiga, Arminda; Jorge, Cláudia; Miltenberger-Miltenyi, Gabriel; Pinto, Fausto J.Introduction: The congenital long QT syndrome (LQTS) is a genetic cardiac channelophathy with variable penetrance characterized by corrected QT (QTc) interval prolongation and predisposition to polymorphic ventricular tachycardia (PVT), which normally presents with syncope or sudden death. It can be caused by mutations in different ion channels, resulting in prolongation of the myocardial repolarization1 . The ...