2 documents found, page 1 of 1
Aberrant crypt foci: endoscopic assessment and cell kinetics characterization
Figueiredo, Pedro; Donato, Maria; Urbano, Marta; Goulão, Helena; Gouveia, Hermano; Sofia, Carlos; Leitão, Maximino; Freitas, DinizAbstract Background and aims Aberrant crypt foci (ACF) are preneoplastic lesions in animal models of colorectal cancer. The aim of the study is to investigate if ACF are involved in human colorectal carcinogenic process and if they can be helpful in predicting the presence of a colorectal neoplasia. Methods The study included, between 2003 and 2005, 182 patients, 62 with adenoma, 55 with colorectal carcinoma, 5...
Secondary biliary cirrhosis in a patient with histiocytosis X.
Romão, Zita; Pontes, J; Andrade, P; Leitão, M C; Donato, A; Freitas, DinizHistiocitose X or Histiocytosis of the Langerhans cells represents a complex spectrum of clinical alterations, resulting from infiltration by anomalous histiocytes of various organs, including the skin, bones, lungs, lymphatic ganglia and liver. Liver disease is rare and the mechanism by which lesions appear is unknown. Cholestasis results from phenomena of sclerosant colangitis, which affects the intrahepatic ...