2 documents found, page 1 of 1
Genetic profiling of Trypanosoma cruzi directly in infected tissues using neste...
Pimenta, Juliana Ramos; Freitas, Jorge Marcelo de; Duffy, Tomás; Bartholomeu, Daniella Castanheira; Oliveira, Riva de Paula; Chiari, EglerThe investigation of the importance of the genetics of Trypanosoma cruzi in determining the clinical course of Chagas disease will depend on precise characterisation of the parasites present in the tissue lesions. This can be adequately accomplished by the use of hypervariable nuclear markers such as microsatellites. However the unilocal nature of these loci and the scarcity of parasites in chronic lesions make...
Further genetic characterization of the two Trypanosoma cruzi Berenice strains ...
Cruz, Ruth Elizabeth; Macedo, Andréa Mara; Barnabé, Christian; Freitas, Jorge Marcelo de; Chiari, Egler; Veloso, Vanja Maria; Carneiro, Cláudia MartinsWe describe here an extension of a previous genetic characterization of Trypanosoma cruzi strains (Be-62 and Be-78) isolated from the patient Berenice, the first human case of Chagas disease [Chagas, C., 1909. Nova Tripanom´ıase humana. Estudos sobre morfologia e o ciclo evolutivo do Schizotrypanum cruzi, n. gen., n. sp., agente etiol´ojico da nova entidade morbida do homem. Mem. Inst. Oswaldo Cruz 1, 159–218]....