Background: Seroepidemiological studies provide estimates of population-level immunity, prevalence/incidence of infections, and evaluation of vaccination programs. We assessed the seroprevalence of protective antibodies against influenza and evaluated the correlation of seroprevalence with the cumulative annual influenza incidence rate. Methods: We conducted an annual repeated cross-sectional seroepidemiologica...
Introduction: Febrile neutropenia (FN) is a potentially severe entity, particularly in hemato-oncologic patients who have higher incidence of colonization with multidrug-resistant bacteria. Discrepancies among guidelines contribute to divergence in antimicrobial practices. Our objective was to assess the variation of practices in antimicrobial therapy in high-risk FN among Portuguese hematologists. Methods: We ...
Objectives Azathioprine (AZA)-induced pancreatitis (AIP) is a common, idiosyncratic adverse effect whose incidence and risk factors data in inflammatory bowel disease (IBD) patients are not fully clarified. We aimed to establish the incidence, clinical course and identify risk factors for AIP. Methods A retrospective study including all IBD patients on AZA between January 2013 and July 2020 was conducted. Patie...
Anemia is a globally widespread condition in women and is associated with reduced economic productivity and increased mortality worldwide. Here we map annual 2000–2018 geospatial estimates of anemia prevalence in women of reproductive age (15–49 years) across 82 low- and middle-income countries (LMICs), stratify anemia by severity and aggregate results to policy-relevant administrative and national levels. Addi...
Diarrhetic shellfish toxins (DSTs) are among the most prevalent marine toxins in Europe’s and in other temperate coastal regions. These toxins are produced by several dinoflagellate species; however, the contamination of the marine trophic chain is often attributed to species of the genus Dinophysis. This group of toxins, constituted by okadaic acid (OA) and analogous molecules (dinophysistoxins, DTXs), are hig...
TiO2 crystallochemical properties have been explored and correlated with the activity of this material in the scavenging of reactive oxygen and nitrogen species (ROS/RNS). It is well known that those highly reactive species are produced by inflammatory cells and neutralized by some oxides, such a titanium dioxide under light. Nevertheless, the mechanism of action of this ceramic material is yet to be fully unde...
Nowadays the development of new testing machines and the optimization of new specimen geometries are two very demanding activities. In order to study complex material stress and strain distributions, as in-plane biaxial loading, one must develop new technical solutions. A new type of testing machine has been developed by the present authors, for the fatigue testing of cruciform specimens, but the low capacity o...
Failure modes and effects analysis is a framework that has been widely used to improve reliability by prioritizing failures modes using the so‐called risk priority number. However, the risk priority number has some problems frequently pointed out in literature, namely its non‐injectivity, non‐surjectivity, and the impossibility to give weights to risk variables. Despite these disadvantages, the risk priority nu...
Composite material usage in aircraft has been rising since the 1990s, with significant increases in manufacturing productivity and repeatability due to automation in the production of aeronautic parts made of composite materials, becoming a strong driver for widespread adoption of composites in this industry. Automated Tape Layup (ATL) and Automated Fibre Placement (AFP) are two of the most important automated ...