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Genotyping and drug resistance patterns of Mycobacterium tuberculosis strains o...

Luiz, Roberta dos Santos Silva; Suffys, Phillip; Barroso, Elizabeth Clara; Kerr, Ligia Regina Franco Sansigolo; Duarte, Cynthia Romariz

Objectives: This study has used a combination of clinical information, spoligotyping, and georeferencing system to elucidate the genetic diversity of the Mycobacterium tuberculosis isolates circulating in a TB-prevalent municipality of Northeast Brazil. Methods: A total of 115 M. tuberculosis strains were isolated from pulmonary tuberculosis patients from January 2007 to March 2008 in Fortaleza. Drug susceptibi...

Date: 2022   |   Origin: Oasisbr

Segurança do uso de terapias biológicas para o tratamento de artrite reumatoide...

Mota, Licia Maria Henrique da; Cruz, Bóris Afonso; Brenol, Claiton Viegas; Pollak, Daniel Feldman; Pinheiro, Geraldo da Rocha Castelar

O tratamento das doenças reumáticas autoimunes sofreu uma progressiva melhora ao longo da última metade do século passado, que foi expandida com a contribuição das terapias biológicas ou imunobiológicos. No entanto, há que se atentar para as possibilidades de efeitos indesejáveis advindos da utilização dessa classe de medicações. A Sociedade Brasileira de Reumatologia (SBR) elaborou um documento, baseado em amp...

Date: 2017   |   Origin: Oasisbr

Impact of iron overload on interleukin-10 levels, biochemical parameters and ox...

Barbosa, Maritza Cavalcante; Santos, Talyta Ellen Jesus dos; Souza, Geane Félix de; Assis, Lívia Coêlho de; Freitas, Max Victor Carioca

Objective: The aim of this study was to evaluate the impact of iron overload on the profile of interleukin-10 levels, biochemical parameters and oxidative stress in sickle cell anemia patients. Methods: A cross-sectional study was performed of 30 patients with molecular diagnosis of sickle cell anemia. Patients were stratified into two groups, according to the presence of iron overload: Iron overload (n = 15) a...

Date: 2014   |   Origin: Oasisbr

Genotyping and drug resistance patterns of Mycobacterium tuberculosis strains o...

Luiza, Roberta dos Santos Silva; Suffys, Phillip; Barroso, Elizabeth Clara; Kerr, Ligia Regina Franco Sansigolo; Duarte, Cynthia Romariz

Objectives: This study has used a combination of clinical information, spoligotyping, and georeferencing system to elucidate the genetic diversity of the Mycobacterium tuberculosis isolates circulating in a TB-prevalent municipality of Northeast Brazil. Methods: A total of 115 M. tuberculosis strains were isolated from pulmonary tuberculosis patients from January 2007 to March 2008 in Fortaleza. Drug susceptibi...

Date: 2014   |   Origin: Oasisbr

Seropositivity to anti-phenolic glycolipid-I in leprosy cases, contacts and no ...

Frota, Cristiane C.; Freitas, Max Victor Carioca; Foss, Norma T.; Lima, Luana N.C.; Rodrigues, Laura C.; Barreto, Maurício L.

The seroprevalence rates of IgM anti-phenolic glycolipid-I (PGL-I) antibodies in four study groups with differing exposure to Mycobacterium leprae in Ceará, Brazil were investigated between March 2005 and August 2006. The first three groups in a high prevalence area included 144 cases of leprosy, their 380 contacts and 317 participants with no known lep- rosy contact. The fourth group in a low prevalence area c...

Date: 2013   |   Origin: Oasisbr



The therapeutic potential of the HLA-G molecule. [Editorial]

Freitas, Max Victor Carioca

Date: 2012   |   Origin: Oasisbr


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