29 documents found, page 1 of 3
From art to insight: The role of a creative arts therapies group workshop on co...
Arriaga, P.; Simões, M. P.; Marques, S.; Freitas, R.; Pinto, H. D.; Prior, M. P.; Candeias, S.; Rodrigues, M.This study examined the effects of a three-hour Creative Arts Therapies (CATs) group workshop on perceived well-being, self-awareness, and loneliness among college students. Using a within-subjects design, participants completed surveys before and after the workshop and during a follow-up phase. Each workshop, facilitated by two certified art therapists, involved groups of 5 to 13 students. The workshops includ...
N-1,2,3-Triazole-Isatin Derivatives: Anti-proliferation effects and target iden...
Busto, N.; Leitão-Castro, J.; García-Sosa, A.T.; Cadete, F.; Marques, C.S.; Freitas, R.; Burke, A.J.Molecular hybridization approaches have become an important strategy in medicinal chemistry, and to this end, we have developed a series of novel N-1,2,3-triazole–isatin hybrids that are promising as tumour anti-proliferative agents. Our isatin hybrids presented high cytotoxic activity against colon cancer cell line SW480, lung adenocarcinoma cell line A549, as well as breast cancer cell lines MCF7 and MDA-MB-2...
Caffeine as a contaminant of concern: a review on concentrations and impacts in...
Vieira, L. R.; Soares, A. M. V. M.; Freitas, R.Caffeine has been identified as emerging contaminant of concern due to its widespread occurrence in the aquatic environment and potential to be biologically active. Recently, these concerns have been translated in an increasing research on its occurrence and effects on biota. However, there is still a limited knowledge on seawater matrices and the implications of caffeine presence in coastal and marine ecosyste...
Ficopomatus enigmaticus larval development assay: an application for toxicity a...
Oliva, M.; Manzini, C.; Pittaluga, G. Bontà; Kozinkova, L.; De Marchi, L.; Freitas, R.; Fabi, G.; Pretti, C.Ficopomatus enigmaticus is a serpulid polychaete, reef-forming, dioecious gamete spawner throughout different seasons and in different salinity conditions. Due to these characteristics, its candidacy as a model organism to monitor both marine and brackish matrices was assessed. Marine sediments collected in a polluted area near the port of Ancona (Italy) were used as case study. Besides the chemical characteriz...
Effects of copper on larvae of the marbled crab Pachygrapsus marmoratus (Decapo...
Oliva, M.; De Marchi, L.; Cuccaro, A.; Casu, V.; Tardelli, F.; Monni, G.; Freitas, R.; Caliani, I.; Fossi, M. C.; Fratini, S.; Baratti, M.; Pretti, C.The importance of trace elements in ecotoxicological investigations is a well-known issue when monitoring polluted areas such as commercial harbors. Copper represents one of the most common metal contaminants, often detected in these areas as it is widely employed in various fields and has many sources of inflow in the marine environment. Pachygrapsus marmoratus is a widespread intertidal crab species that has ...
Pollution effects on biochemical pathways determined in the polychaete Hediste ...
Nunes, B.; Vidal, D.; Barbosa, I.; Soares, A. M. V. M.; Freitas, R.Biomonitoring is an important tool for the assessment of the quality and functions of ecosystems, providing information about the pollutants present and the direct effects that they exert on organisms. Biomonitoring relies upon the quantification of variables that can be biochemical, genetic, morphological and physiological changes. Such variables are designated as biomarkers, and multiple biomarkers are usuall...
Evolving hallmarks in urothelial bladder cancer: unveiling potential biomarkers
Afonso, Julieta Alexandra Pereira; Freitas, R.; Lobo, F.; Morais, A.; Amaro, T.; Reis, R. M.; Baltazar, Fátima; Longatto Filho, Adhemar; Santos, L.Urothelial bladder carcinoma (UBC), the most frequent type (90%) of bladder cancer and the second most common malignancy of the urogenital region, is a relatively well understood type of cancer, with numerous studies concerning pathogenetic pathways, natural history and bladder tumor biology being reported. Despite this, it continues to remain a challenge in the oncology field, mostly due to its relapsing and p...
Review: bucephalus minimus, a deleterious trematode parasite of cockles Cerasto...
Magalhães, L.; Freitas, R.; de Montaudouin, X.Trematodes are the most prevalent and abundant macroparasites in coastal waters. They display a complex life cycle with alternation of free-living and parasitic stages generally involving three host species. The most deleterious stage is in the first intermediate host (a mollusc) where the parasite penetrates as miracidium larvae and asexually multiplicates in sporocysts/rediae to provide cercariae larvae. Howe...
Trematode communities in cockles (Cerastoderma edule) of the Ria de Aveiro (Por...
Freitas, R.; Martins, R.; Campino, B.; Figueira, E.; Soares, A. M. V. M.; Montaudouin, X.This work aims to assess the trematode parasites infecting the edible cockle Cerastoderma edule, collected in the Ria de Aveiro lagoon, one of the most relevant biodiversity hotspots of the Western Iberia, and evaluate the relationship between the observed patterns and environmental descriptors. A total of 11 of the 16 trematode species known to infect C. edule were identified, including Himasthla continua and ...
Modeling of chlorine decay in drinking water supply systems using EPANET MSX
Monteiro, L.; Figueiredo, D.; Dias, S.; Freitas, R.; Covas, D.; Menaia, J.; Coelho, S. T.The modelling of chlorine residual in water supply systems is of great importance in managing disinfectant concentrations throughout the network. First order decay kinetics are currently often used to describe both bulk and wall chlorine consumption. However, more complex approaches have been proposed, namely a parallel, two-reactant second order decay model (2R model) that has been reported as yielding better ...