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Evaluation of determinants of food waste in family households in the greater po...

Portugal, T; Freitas, S; Cunha, LM; Rocha, Ada

Despite food waste occurring along the entire food supply chain, a significant proportion occurs in domestic settings. Large quantities of domestic food waste have been attributable to consumer behaviors during buying, cooking, consumption, and disposal. The main objective of this research was to understand the major determinants of household food waste from families in the north of Portugal. A convenience samp...


Chemistry, bioactivity and biosynthesis of cyanobacterial alkylresorcinols

Martins, T.P.; Rouger, C; Glasser, N.R; Freitas, S; De Fraissinette, N.B; Balskus, E.P; Tasdemir, D; Leão, P.N.

Covering: up to 2019 Alkylresorcinols are amphiphilic metabolites, well-known for their diverse biological activities, produced by both prokaryotes and eukaryotes. A few classes of alkylresorcinol scaffolds have been reported from the photoautotrophic cyanobacteria, ranging from the relatively simple hierridins to the more intricate cylindrocyclophanes. Recently, it has emerged that cyanobacteria employ two dif...


Role of alpha-1 antitrypsin genotypes in the progression of adult liver disease

Pereira, Vítor Magno; Gaspar, R; Simões, C; Maia, L.; Costa, C; Carvão, J; Oliveira, G; Serrão, G; Jesus, V; Sucena, M.C; Santos, C; Gomes, J; Lages, J


Aphasia Rapid Test: Translation, Adaptation and Validation Studies for the Port...

Tábuas-Pereira, M; Freitas, S; Beato-Coelho, J; Ribeiro, JA; Parra, J; Martins, C; Silva, M; Matos, MA; Nogueira, AR; Silva, F; Sargento-Freitas, J

Classical aphasia evaluation scales are too long to use in the context of acute stroke or as a monitoring tool. The Aphasia Rapid Test is a 26-point scale developed as a bedside assessment to rate aphasia severity in acute stroke patients in less than 3 minutes. We aimed to adapt and validate this scale for European Portuguese.


The Montreal Cognitive Assessment (MoCA) as a screening test for cognitive dysf...

Freitas, S; Batista, SJ; Afonso, AC; Simões, MR; de Sousa, L; Cunha, L; Santana, I

This study investigates the utility of the Portuguese version of Montreal Cognitive Assessment (MoCA) as a screening-method for identifying cognitive dysfunction (CD) in multiple sclerosis (MS). The 118 participants with comprehensive neuropsychological assessment were divided into two subgroups: (I) MS group (n = 59) and (II) control group (n = 59). The MS patients were classified as cognitively intact (n = 26...


Discriminative capacity and construct validity of the Clock Drawing Test in Mil...

Duro, D; Freitas, S; Tábuas-Pereira, M; Santiago, B; Botelho, MA; Santana, I

OBJECTIVES: The aim of this study was to analyze the psychometric and diagnostic properties of the Clock Drawing Test (CDT), scored according to the Babins, Rouleau, and Cahn scoring systems, for Mild Cognitive Impairment (MCI) and Alzheimer's disease (AD) screening, and develop corresponding cutoff scores. Additionally, we assessed the construct validity of the CDT through exploratory and confirmatory factor a...


Self-Assembled Monolayers for Dental Implants

Freitas, S; Correa-Uribe, A; Martins, MCL; Pelaez-Vargas, A

Implant-based therapy is a mature approach to recover the health conditions of patients affected by edentulism. Thousands of dental implants are placed each year since their introduction in the 80s. However, implantology faces challenges that require more research strategies such as new support therapies for a world population with a continuous increase of life expectancy, to control periodontal status and new ...


Arabidopsis thaliana SPF1 and SPF2 are nuclear-located ULP2-like SUMO proteases...

Castro, P; Santos, M; Freitas, S; Cana-Quijada, P; Lourenço, T; Rodrigues, M; Fonseca, F; Ruiz-Albert, J; Azevedo, JE; Tavares, R; Castillo, A

Post-translational modifiers such as the small ubiquitin-like modifier (SUMO) peptide act as fast and reversible protein regulators. Functional characterization of the sumoylation machinery has determined the key regulatory role that SUMO plays in plant development. Unlike components of the SUMO conjugation pathway, SUMO proteases (ULPs) are encoded by a relatively large gene family and are potential sources of...


Soft Lithography and Minimally Human Invasive Technique for Rapid Screening of ...

Alvarez-Escobar, M; Freitas, S; Hansford, D; Monteiro, FJ; Pelaez-Vargas, A

Introduction. Microfabrication offers opportunities to study surface concepts focused to reduce bacterial adhesion on implants using human minimally invasive rapid screening (hMIRS). Wide information is available about cell/biomaterial interactions using eukaryotic and prokaryotic cells on surfaces of dental materials with different topographies, but studies using human being are still limited. Objective. To ev...


Idiopathic Pulmonary Fibrosis in the Era of Antifibrotic Therapy: Searching for...

Robalo-Cordeiro, C; Campos, P; Carvalho, L; Borba, A; Clemente, S; Freitas, S; Furtado, S; Jesus, JM; Leal, C; Marques, A; Melo, N; Souto-Moura, C

Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal lung disease that up to now has been associated with a poor prognosis. However, the results of the INPULSIS and ASCEND trials and the approval of nintedanib and pirfenidone have marked the beginning of a new era for IPF patients. Questions remain, however. Should these drugs be used earlier? What effect will they have on more severe disease? Will th...


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