32 documents found, page 1 of 4
Association of Obesity-Related Genetic Variants with Android Fat Patterning and...
Sá, Débora; Mendonça, Maria Isabel; Sá, Débora; Sousa, Francisco; Abreu, Gonçalo; Ferreira, Matilde; Henriques, Eva; Freitas, Sónia; Rodrigues, MarianaBackground/Objectives: The location and distribution of excess fat, rather than overall adiposity, are stronger predictors of cardiometabolic risk and are commonly assessed using the waist-to-hip ratio (WHR). Fat distribution in women has a heritable component, yet the genetic factors that influence it remain poorly understood. We aim to assess the association between obesity-related polymorphisms with WHR and ...
Unraveling the genetic basis of subclinical atherosclerosis
Sá, Débora; Mendonça, Maria Isabel; Serrão, Marco; Sousa, Francisco; Abreu, Gonçalo; Henriques, Eva; Borges, Sofia; Freitas, Sónia; Rodrigues, MarianaIntroduction and objectives: Decoding the genetic basis of coronary artery disease (CAD) through an intermediate phenotype – coronary calcification – can help us to better understand this deadly disease and enable the creation of better therapeutic strategies. This work aims to assess the relationship between a set of single nucleotide polymorphisms (SNPs) previously associated with CAD and coronary artery calc...
Validation of the SCORE2 risk prediction algorithm in a Portuguese population
Temtem, Margarida; Mendonça, Maria Isabel; Santos, Marina; Sá, Débora; Sousa, Francisco; Freitas, Sónia; Borges, Sofia; Henriques, EvaIntroduction and Objectives: Subjects without cardiovascular (CV) disease (CVD) may suffer from subclinical atherosclerosis, and are at increased risk for atherosclerotic CV events (ASCVE). The ESC/EAS risk SCORE was updated by SCORE2, which estimates 10-year risk of fatal and non-fatal CVD in European populations aged 40–69 years without established CVD or diabetes. Our aim was to compare the two ESC/EAS risk ...
Satisfação do cliente da Região Autónoma da Madeira alvo de cuidados de enferma...
Freitas, Sónia; Gouveia, B.R.; Jesus, Élvio Henriques De; Bettencourt, MeríciaEnquadramento: A satisfação com os cuidados de saúde prestados à pessoa, é considerada um importante indicador no domínio da qualidade dos cuidados, baseada na perceção e valorização dos cuidados que lhe são prestados, considerando as suas necessidades e expetativas. Como indicador permite monitorizar a qualidade dos serviços de saúde, com repercussões na sua planificação, avaliação e melhoria contínua. Objetiv...
SATISFACTION OF CLIENTS FROM THE AUTONOMOUS REGION OF MADEIRA RECEIVING REHABIL...
Freitas, Sónia; Gouveia, Bruna; Henriques de Jesus, Élvio; Gouveia Rodrigues Bettencourt Jesus, Maria MeríciaBackground: Satisfaction with the care provided to the person is considered an important indicator of quality of care, based on the perception and appreciation of the care provided to the person, considering his/her needs and expectations. As an indicator, it allows monitoring the quality of health services, with repercussions in their planning, evaluation and continuous improvement. Objective: To assess the le...
Epicardial adipose tissue is a promising imaging biomarker of subclinical ather...
Mendonça, Maria Isabel; Sousa, João Adriano; Serrão, Marco; Santos, Marina; Temtem, Margarida; Sá, Débora; Sousa, Francisco; Henriques, EvaIdentifying markers to discriminate high and low-risk individuals better is essential. Coronary Calcium Score (CAC) is an established marker of subclinical atherosclerosis. Epicardial Adipose Tissue (EAT), a new imaging biomarker, has shown considerable interest in the scientific community.
Genetic information improves the prediction of major adverse cardiovascular eve...
Mendonca, Maria Isabel; Henriques, Eva; Borges, Sofia; Sousa, Ana Célia; Pereira, Andreia; Santos, Marina; Temtem, Margarida; Freitas, SóniaThe inclusion of a genetic risk score (GRS) can modify the risk prediction of coronary artery disease (CAD), providing an advantage over the use of traditional models. The predictive value of the genetic information on the recurrence of major adverse cardiovascular events (MACE) remains controversial. A total of 33 genetic variants previously associated with CAD were genotyped in 1587 CAD patients from the GENE...
Epicardial Adipose Tissue: The Genetics Behind an Emerging Cardiovascular Risk ...
Sousa, João Adriano; Mendonca, Maria Isabel; Serrão, Marco; Borges, Sofia; Henriques, Eva; Freitas, Sónia; Tentem, Margarida; Santos, MarinaEvidence points epicardial adipose tissue (EAT) as an emerging cardiovascular risk marker. Whether genetic polymorphisms linked with atherosclerosis are associated with higher EAT is still unknown. We aim to assess the role of genetic burden of atherosclerosis and its association to EAT in a cohort of asymptomatic individuals without coronary disease. A total of 996 participants were prospectively enrolled in a...
Epicardial Adipose Tissue
Sousa, João Adriano; Mendonça, Maria Isabel; Serrão, Marco; Borges, Sofia; Henriques, Eva; Freitas, Sónia; Tentem, Margarida; Santos, MarinaEvidence points epicardial adipose tissue (EAT) as an emerging cardiovascular risk marker. Whether genetic polymorphisms linked with atherosclerosis are associated with higher EAT is still unknown. We aim to assess the role of genetic burden of atherosclerosis and its association to EAT in a cohort of asymptomatic individuals without coronary disease. A total of 996 participants were prospectively enrolled in a...
Polimorfismos Genéticos Associados ao Aparecimento de Hipertensão Arterial Numa...
Sousa, Ana Célia; Palma dos Reis, Roberto; Pereira, Andreia; Borges, Sofia; Freitas, Ana Isabel; Guerra, Graça; Gouveia, Sara; Góis, TeresaIntrodução: A hipertensão arterial é uma doença complexa, multifatorial, controlada por fatores genéticos e ambientais. Objetivo: Avaliar a susceptibilidade genética no aparecimento de hipertensão arterial e sua associação com os fatores de risco tradicionais na eclosão desta patologia. Material e Métodos: Estudo caso-controlo com 1712 indivíduos, idade média de 51,0 ± 7,9 anos (860 hipertensos e 852 controlos)...