Hypersensitivity pneumonitis is a complex interstitial lung syndrome and is associated with significant morbimortality, particularly for fibrotic disease. This condition is characterized by sensitization to a specific antigen, whose early identification is associated with improved outcomes. Biomarkers measure objectively biologic processes and may support clinical decisions. These tools evolved to play a crucia...
Introduction Wilson's disease (WD) is a rare and underdiagnosed genetic disorder caused by anomalous tissue copper deposition, and for which epidemiological studies, specifically in Portugal, are scarce. Objectives This study aimed to evaluate the prevalence and incidence of WD and provide a description of its main clinical and laboratory features. Methods A retrospective study was carried out, with a search be...
Nas páginas seguintes são apresentados, de forma detalhada, os resultados do inquérito promovido pela Lisboa E-Nova – Agência de Energia e Ambiente de Lisboa e realizado pelo Instituto de Saúde Ambiental da Faculdade de Medicina da Universidade de Lisboa, com a colaboração também do Instituto de Ciências Sociais da Universidade de Lisboa, sobre conforto térmico autorrelatado e sua associação com indicadores com...
Coffee leaf rust (CLR), a disease caused by the biotrophic fungus Hemileia vastatrix (Hv), is the main threat to the worldwide production of Arabica coffee. The gradual breakdown of resistance in coffee varieties in the last years has highlighted the need for novel sources of resistance to CLR. This work aimed to unveil the cellular and molecular resistance profile of the Kawisari hybrid (C. arabica x C. liberi...
Introduction: Rheumatoid arthritis (RA) is a disabling autoimmune disease. Biological agents have dramatically altered the natural course of the disease. This study evaluated the impact of these drugs on patients’ lives and analyzed the factors responsible for a better response to treatment.Material and Methods: Retrospective study of 80 patients diagnosed with RA and treated with biological drugs between Janua...
This text presents the dossier Bourgeoisie and extreme right in Brazil. A dossier about this theme becomes necessary in Brazil due to the rise of the extreme right and the election of the Bolsonaro administration. In this process, it is possible to identify a trend: the cooption of extreme-right movements by the bourgeoisie. As a political movement traditionally originate din the middle sectors of capitalist so...
The ubiquitin-like modifying peptide SMALL UBIQUITIN-LIKE MODIFIER (SUMO) has become a known modulator of the plant response to multiple environmental stimuli. A common feature of many of these external stresses is the production of reactive oxygen species (ROS). Taking into account that SUMO conjugates rapidly accumulate in response to an external oxidative stimulus, it is likely that ROS and sumoylation conve...
O presente artigo nasce como resultado da escuta de várias comunicações no âmbito do Centenário de Paulo Freire em conjunto com leituras que foram sendo feitas para a minha tese de Doutoramento, nascendo de um encontro feliz entre ambas as atividades. Não é possível ver apenas um Educador, um Filosofo ou um Sociólogo, nem também ver em Paulo Freire um Museólogo Social. Paulo Freire assume-se como um homem compl...