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Optimization of production, biochemical characterization and In Vitro evaluatio...

de Souza, Fabiana América Silva Dantas; Sales, Amanda Emmanuelle; Costa e Silva, Pablo Eugênio; Bezerra, Raquel Pedrosa

The capacity of fibrinolytic enzymes to degrade blood clots makes them of high relevance in medicine and in the pharmaceutical industry. In this work, forty-three microorganisms of the genus Bacillus were evaluated for their potential to produce fibrinolytic proteases. Thirty bacteria were confirmed as producers of fibrinolytic enzymes, the best results obtained for the strain Bacillus amyloliquefaciens UFPEDA ...


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