8 documents found, page 1 of 1
Ultrasensitive dopamine detection with graphene aptasensor multitransistor arrays
Abrantes, Mafalda; Rodrigues, Diana; Domingues, Telma; Nemala, Siva S; Monteiro, Patricia; Borme, Jérôme; Alpuim, P.; Jacinto, LuisDetecting physiological levels of neurotransmitters in biological samples can advance our understanding of brain disorders and lead to improved diagnostics and therapeutics. However, neurotransmitter sensors for real-world applications must reliably detect low concentrations of target analytes from small volume working samples. Herein, a platform for robust and ultrasensitive detection of dopamine, an essential...
Hybrid multisite silicon neural probe with integrated flexible connector for in...
Novais, Ashley; Calaza, Carlos; Fernandes, José; Fonseca, Helder; Monteiro, Patricia; Gaspar, João; Jacinto, Luís Ricardo MonteiroMultisite neural probes are a fundamental tool to study brain function. Hybrid silicon/polymer neural probes combine rigid silicon and flexible polymer parts into one single device and allow, for example, the precise integration of complex probe geometries, such as multishank designs, with flexible biocompatible cabling. Despite these advantages and benefiting from highly reproducible fabrication methods on bot...
Double-layer flexible neural probe with closely spaced electrodes for high-dens...
Pimenta, Sara Filomena Ribeiro; Rodrigues, José A.; Machado, Francisca; Ribeiro, João F.; Maciel, Marino Jesus Correia; Bondarchuk, OleksandrFlexible polymer neural probes are an attractive emerging approach for invasive brain recordings, given that they can minimize the risks of brain damage or glial scaring. However, densely packed electrode sites, which can facilitate neuronal data analysis, are not widely available in flexible probes. Here, we present a new flexible polyimide neural probe, based on standard and low-cost lithography processes, wh...
The exceptional finding of Locus 2 at Dehesilla Cave and the Middle Neolithic r...
García Rivero, Daniel; Taylor, Ruth; Umbelino, Cláudia; Price, T. Douglas; García-Viñas, Esteban; Bernáldez-Sánchez, Eloísa; Pérez-Jordà, GuillemThere is a significant number of funerary contexts for the Early Neolithic in the Iberian Peninsula, and the body of information is much larger for the Late Neolithic. In contrast, the archaeological information available for the period in between (ca. 4800-4400/4200 cal BC) is scarce. This period, generally called Middle Neolithic, is the least well-known of the peninsular Neolithic sequence, and at present th...
Residents' involvement in city brand co-creation and their perceptions of city ...
Casais, Beatriz Graça Luz; Monteiro, PatriciaThis study discusses residents' involvement in the co-creation of a city brand, their perceptions about brand identity and authenticity and the fit with their sense of place. The city of Porto, Portugal, was chosen as a case study, since a new city brand was created in September 2014. The authors analysed the descriptive book explaining the strategy of the city brand created. In order to understand residents' i...
Shell we cook it? An experimental approach to the microarchaeological record of...
Aldeias, Vera; Gur-Arieh, Shira; Maria, Raquel; Monteiro, Patricia; Cura, PedroIn this paper, we investigate the microarchaeological traces and archaeological visibility of shellfish cooking activities through a series of experimental procedures with direct roasting using wood-fueled fires and controlled heating in a muffle furnace. An interdisciplinary geoarchacological approach, combining micromorphology, FTIR (in transmission and ATR collection modes), TGA and XRD, was used to establis...
Morphology of secretory structures and essential oil composition in Mentha cerv...
Rodrigues, Leandra; Monteiro, Patricia; Póvoa, Orlanda; Teixeira, Generosa; Moldão, Margarida; Figueiredo, Ana Cristina; Monteiro, AnaABSTRACT: Mentha cervina L. is an aromatic plant that is traditionally used in the Alentejo region of Portugal to flavour food dishes and for the medicinal properties of the essential oil produced in its glandular trichomes. The morphology and distribution of the secretory structures of 20 populations was studied by light and scanning electron microscopy and revealed a great similarity in the type and distribut...
Morphology of secretory structures and essential oil composition in Mentha cerv...
Rodrigues, Leandra; Monteiro, Patricia; Povoa, OrIanda; Teixeira, Generosa; Moldão, Margarida; Figueiredo, Ana Cristina; Monteiro, AnaMentha cervina L. is an aromatic plant that is traditionally used in the Alentejo region of Portugal to flavour food dishes and for the medicinal properties of the essential oil produced in its glandular trichomes. The morphology and distribution of the secretory structures of 20 populations was studied by light and scanning electron microscopy and revealed a great similarity in the type and distribution of gla...