3 documents found, page 1 of 1
Analysis of salivary levels of IL-1β, IL17A, OPG and RANK-L in periodontitis us...
Relvas, Marta; Silvestre, Ricardo Jorge Leal; Gonçalves, Maria; Cabral, Cristina; Frias, Ana Isabel Mendes; Monteiro, Luís; Viana da Costa, AlexandraPeriodontitis is a chronic disease with a high overall prevalence. It involves a complex interplay between the immune-inflammatory pathways and biofilm changes, leading to periodontal attachment loss. The aims of this study were (i) to assess whether the salivary IL-1β, IL-17A, RANK-L and OPG levels have the potential to discriminate between the mild and severe periodontitis conditions; and (ii) to enable diagn...
Immune tumor microenvironment in ovarian cancer ascites
Almeida-Nunes, Diana Luísa; Frias, Ana Isabel Mendes; Silvestre, Ricardo Jorge Leal; Dinis-Oliveira, Ricardo Jorge; Ricardo, SaraOvarian cancer (OC) has a specific type of metastasis, via transcoelomic, and most of the patients are diagnosed at advanced stages with multiple tumors spread within the peritoneal cavity. The role of Malignant Ascites (MA) is to serve as a transporter of tumor cells from the primary location to the peritoneal wall or to the surface of the peritoneal organs. MA comprise cellular components with tumor and non-t...
Relatório de estágio : mestrado em análises clínicas
Frias, Ana Isabel MendesRelatório de estágio no âmbito do Mestrado em Análises Clínicas, apresentado à Faculdade de Farmácia da Universidade de Coimbra; As Análises Clínicas representam uma importante ferramenta para o diagnóstico e seguimento de muitas patologias. Vários estudos internacionais apontam que setenta por cento (70%) da tomada da decisão clínica médica está dependente de, ou é confirmada por, resultados de testes médicos ...