14 documents found, page 1 of 2
Genotyping and drug resistance patterns of Mycobacterium tuberculosis strains o...
Luiz, Roberta dos Santos Silva; Suffys, Phillip; Barroso, Elizabeth Clara; Kerr, Ligia Regina Franco Sansigolo; Duarte, Cynthia RomarizObjectives: This study has used a combination of clinical information, spoligotyping, and georeferencing system to elucidate the genetic diversity of the Mycobacterium tuberculosis isolates circulating in a TB-prevalent municipality of Northeast Brazil. Methods: A total of 115 M. tuberculosis strains were isolated from pulmonary tuberculosis patients from January 2007 to March 2008 in Fortaleza. Drug susceptibi...
Molecular characterization of pre-extensive drug resistant Mycobacterium tuberc...
Campelo, Thales Alves; Lima, Luana Nepomuceno Costa; Lima, Karla Val?ria Batista; Silva, Caroliny Soares; Concei??o, Mar?lia Lima daThis work was supported by Funda??o Cearense de Apoio ao Desenvolvimento Cient?fico e Tecnol?gico - FUNCAP (grant N? 178638234); and the Coordena??o de Aperfei?oamento de Pessoal de N?vel Superior - Brasil (CAPES) - Finance Code 001.; Universidade Federal do Cear?. Faculdade de Medicina. Departamento de Patologia e Medicina Legal. Fortaleza, CE, Brazil.; Minist?rio da Sa?de. Secretaria de Vigil?ncia em Sa?de. I...
Molecular characterization of pre-extensive drug resistant Mycobacterium tuberc...
Campelo, Thales Alves; Lima, Luana Nepomuceno Costa; Lima, Karla Valéria Batista; Silva, Caroliny Soares; Conceição, Marília Lima daIn Fortaleza, the capital of Ceara State, Brazil, the detection rate of tuberculosis (TB) in 2018 was 65.5/100,000 inhabitants with a cure rate of 59.1%, which is higher than the country average. This study investigated the risk factors associated with drug-resistant tuberculosis (DR-TB) and identified the drug-resistance phenotype and resistance-conferring mutations. The geographic distribution of DR-TB in For...
Evaluation of the antimicrobial activity of Cinnamomum zeylanicum essential oil...
Mota, Aquiles Paulino Peres; Campelo, Thales Alves; Frota, Cristiane CunhaThe essential oil (EO) extracted from the bark of Cinnamomum zeylanicum (Czey; also known as cinnamon), mostly derives its properties from its major compound trans-cinnamaldehyde (TCin). The present study evaluated the antimycobacterial activity of the essential oil from Czey (CzeyEO) and TCin against sensitive and resistant clinical isolates of Mycobacterium tuberculosis, as well as the combinatorial effects o...
Efeitos da associação de sinergismo entre o óleo essencial de cinnamomum zeylan...
Mota, Aquiles Paulino Peres; Campelo, Thales Alves; Frota, Cristiane CunhaO aumento contínuo dos casos de resistência do Mycobacterium tuberculosis se tornou um grande obstáculo para o controle efetivo da tuberculose (TB) no mundo. Acredita-se que as plantas medicinais, através dos óleos essenciais (OEs), sejam as melhores alternativas para descoberta de novos fármacos, como o OE extraído da casca de Cinnamomum zeylanicum (OECzey), popularmente conhecida com canela. Uma das alternati...
Genotyping comparison of Mycobacterium leprae isolates by VNTR analysis from na...
Lima, Luana Nepomuceno Costa; Frota, Cristiane Cunha; Suffys, Philip Noel; Fontes, Amanda Nogueira Brum; Mota, Rosa Maria SalaniConselho Nacional de Desenvolvimento Cient?fico e Tecnol?gico, Brazil under [grant number CNPq?410573/2006-0].; Federal University of Cear?. Faculdade de Medicina. Departamento de Patologia e Medicina Legal. Fortaleza, CE, Brazil / Minist?rio da Sa?de. Secretaria de Vigil?ncia em Sa?de. Instituto Evandro Chagas. Ananindeua, PA, Brasil.; Federal University of Cear?. Faculdade de Medicina. Departamento de Patolog...
Natural environmental water sources in endemic regions of northeastern Brazil a...
Arraes, Maria Luisa Bezerra de Macedo; Holanda, Ma?sa Viana de; Lima, Luana Nepomuceno Gondim Costa; Sabadia, Jos? Ant?nio Beltr?oUniversidade Federal do Cear?. Faculdade de Medicina. Departamento de Patologia e Medicina Legal. Fortaleza, CE, Brasil.; Universidade Federal do Cear?. Faculdade de Medicina. Departamento de Patologia e Medicina Legal. Fortaleza, CE, Brasil.; Minist?rio da Sa?de. Secretaria de Vigil?ncia em Sa?de. Instituto Evandro Chagas. Ananindeua, PA, Brasil.; Universidade Federal do Cear?. Departamento de Geologia. Fortal...
Association of breast cancer with human papillomavirus (HPV) infection in North...
Cavalcante, Jos? Roosevelt; Pinheiro, Luiz Gonzaga Porto; Almeida, Paulo Roberto Carvalho de; Ferreira, M?rcia Val?ria Pitombeira; Cruz, Gizele AlmadaUniversidade Federal Cear?. Faculdade de Medicina. Departamento de Cirurgia e Maternidade Escola Assis Chateaubriand. Fortaleza, CE, Brasil.; Universidade Federal Cear?. Faculdade de Medicina. Departamento de Cirurgia e Maternidade Escola Assis Chateaubriand. Fortaleza, CE, Brasil.; Universidade Federal Cear?. Faculdade de Medicina. Departamento de Patologia e Medicina Legal. Fortaleza, CE, Brasil.; Universidad...
Natural environmental water sources in endemic regions of northeastern Brazil a...
Arraes, Maria Luisa Bezerra de Macedo; Holanda, Maísa Viana de; Lima, Luana Nepomuceno Gondim Costa; Sabadia, José Antonio BeltrãoBACKGROUND The detection of live Mycobacterium leprae in soil and animals other than humans suggests that the environment plays a role in the transmission of leprosy. OBJECTIVE The objective of this study was to investigate the presence of viable M. leprae in natural water sources used by the local population in five municipalities in the state of Ceará, northeastern Brazil. METHODS Samples were collected from ...
Presence of Mycobacterium leprae genotype 4 in environmental waters in Northeas...
Holanda, Maísa Viana de; Marques, Livia Erika Carlos; Macedo, Maria Luisa Bezerra de; Pontes, Maria Araci de Andrade; Sabadia, José Antonio BeltrãoINTRODUCTION: This study quantified Mycobacterium leprae bacilli in environmental water samples from five municipalities in the State of Ceará by quantitative polymerase chain reaction (qPCR) and compared the identified genotypes with those obtained from leprosy patient biopsies. METHODS: We collected five replicas from each of the 30 selected reservoirs and skin lesion biopsies from 25 new leprosy cases treate...