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Prolonged maternal separation induces undernutrition and systemic inflammation ...

Figueiredo, Ítalo Leite; Frota, Priscila B.; Cunha, Davi G. da; Raposo, Ramon da Silva; Canuto, Kildere M.; Andrade, Geanne M. de; Sousa, Nuno

Objective: Prolonged maternal separation (PMS) in the first 2 wk of life has been associated with poor growth with lasting effects in brain structure and function. This study aimed to investigate whether PMS-induced undernutrition could cause systemic inflammation and changes in nutrition-related hormonal levels, affecting hippocampal structure and neurotransmission in C57BL/6J suckling mice. Methods: This stud...


Zinc treatment ameliorates diarrhea and intestinal inflammation in undernourish...

Queiroz, Camila A. A. de; Fonseca, Said Gonçalves C.; Frota, Priscila B.; Figueiredo, Ítalo L.; Aragão, Karoline Sabóia; Magalhães, Carlos Emanuel C.

Background: WHO guidelines recommend zinc supplementation as a key adjunct therapy for childhood diarrhea in developing countries, however zinc’s anti-diarrheal effects remain only partially understood. Recently, it has been recognized that low-grade inflammation may influence stunting. In this study, we examined whether oral zinc supplementation could improve weight, intestinal inflammation, and diarrhea in un...

Date: 2014   |   Origin: Oasisbr

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