4 documents found, page 1 of 1
The effect of neoadjuvant platinum-based chemotherapy in BRCA mutated triple ne...
Caramelo, Olga L.; Silva, Cristina M.; Caramelo, Francisco; Frutuoso, Cristina; Almeida-Santos, TeresaBackground: Triple negative breast cancers (TNBC) are associated with an aggressive clinical course, earlier recurrence and short survival. BRCA – mutated tumours represent up to 25% of all TNBC. BRCA status is being studied as a predictive biomarker of response to platinum agents. However, the predictive role of BRCA status is still uncertain in this setting. Since TNBC is a very heterogeneous group of disease...
Cancro Ginecológico – consensos nacionais 2013
Pregal, Alexandra; Sofia, Alexandra Rico; Petiz, Almerinda; Félix, Ana; Jorge, Ana Francisca; Costa, Ana Marta; Lagoa, António; Alves, Boaventura
Dysmenorrhea in adolescents and young adults: prevalence, related factors and l...
Rodrigues, Ana Cláudia; Gala, Sónia; Neves, Ângela; Pinto, Conceição; Meirelles, Cláudia; Frutuoso, Cristina; Vítor, Maria EliseteTo determine the prevalence of dysmenorrhea, limitations in daily living and health care use due to menstrual pain.Observational transversal study of 274 adolescents and young adults (age ≤ 26) who had menstruated in the six months prior to the study, assisted at a Primary Health Care Center. Data were obtained by a 24-item anonymous questionnaire, which included questions about socio-demographic variables, men...
Carcinima de pequenas células do ovário do tipo hipercalcémico - Caso clínico
Domingues, Ana Patrícia; Marinho, Carol; Frutuoso, Cristina; Freire-de-Oliveira, CarlosSmall cell carcinoma of the ovary is a rare tumour that typically affects young women (mean age of 24 years). In two-thirds of cases it courses with hypercalcaemia and has a very reserved prognosis. Due to its rarity, optimal treatment is not consensual, but most 5-year survivors were submitted to a combination of surgery, adjuvant chemo and radiotherapy. The authors report a case of a 13 year old girl who pres...