3 documents found, page 1 of 1
In vitro initial immune response against Leishmania amazonensis infection is ch...
Coêlho, Zirlane Castelo B; Teixeira, Maria Jania; Mota, Erika Freitas; Frutuoso, Mércia Sindeaux; Silva, João Santana da; Barral, AldinaThe initial encounter of Leishmania with its host’s immune system is important in the outcome of infection. Previous studies have shown that PBMCs from healthy volunteers (HV) exposed to Leishmania differ in IFN-γ production. We have expanded such observations evaluating the profi le and kinetics of cytokines (IFN-γ, IL-12p70, IL-10, IL-13), chemokines (CCL5, CCL3, CCL4, CXCL10), and chemokine receptors (CCR1,C...
Efeito adjuvante da lectina de Canavalia brasiliensis no tratamento de Leishman...
Frutuoso, Mércia SindeauxFRUTUOSO, Mércia Sindeaux. Efeito adjuvante da lectina de Canavalia brasiliensis no tratamento de Leishmaniose cutânea experimental. 2016. 117 f. Tese (Doutorado em Biotecnologia) - Universidade Federal do Ceará, Fortaleza, 2017.; The leishmaniases are importante public health problem, comprising a very wide spectrum of clinical presentations. The host protection and cure, depend on his or her capacity to mount...
Avaliação do mecanismo de modulação da resposta imunológica à Leishmaniose visc...
Frutuoso, Mércia SindeauxIntroduction: Visceral leishmaniasis is a serious public health problem in several parts of the developing world. In leishmaniasis, protection and healing correlate with the development of Th1 immune response, and IFN-γ is considered a key molecule in this response. In contrast, the Th2 response results in disease progression. It is noteworthy that after contact with Leishmania the production of IFN-γ differs b...