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Exploring Early Detection of Frailty Syndrome in Older Adults: Evaluation of Ox...

Teixeira-Gomes, Armanda; Laffon, Blanca; Valdiglesias, Vanessa; Gostner, Johanna M.; Felder, Thomas; Costa, Carla; Madureira, Joana; Fuchs, Dietmar

Ageing is accompanied with a decline in several physiological systems. Frailty is an age-related syndrome correlated to the loss of homeostasis and increased vulnerability to stressors, which is associated with increase in the risk of disability, comorbidity, hospitalisation, and death in older adults. The aim of this study was to understand the relationship between frailty syndrome, immune activation, and oxid...


Exploring the potential relation between immune biomarkers and frailty syndrome...

teixeira-gomes, Armanda; Costa, Solange; lage, Bruna; Fuchs, Dietmar; Valdiglesias, Vanessa; Laffon, Blanca; Teixeira, João Paulo

Objectives: On this basis, the main objective of the present work was to evaluate the possible association between immunological: biomarkers and the frailty status in a group of community dwellers.


Assessment of immunotoxicity parameters in individuals occupationally exposed t...

García-Lestón, Julia; Roma-Torres, Joana; Mayan, Olga; Schroecksnadel, Sebastian; Fuchs, Dietmar; Moreira, Ana; Pásaro, Eduardo; Méndez, Josefina

Although adverse health effects produced by lead (Pb) have long been recognized, studies regarding the immunotoxic effects of occupational exposure report conflicting results. In a previous study, alterations in some immunological parameters were noted in 70 Pb-exposed workers. In view of these results, it was of interest to extend this study comprising a larger population and increasing the number of immunolog...


NanoLINEN: Nanotoxicology Link Between India and European Nations

Dhawan, Alok; Shanker, Rishi; Laffon, Blanca; Tajes, Juan Fernandez; Fuchs, Dietmar; van der Laan, Gert; van Broekhuizen, Pieter; Becker, Heidi

Nanotoxicology link between India and European Nations (NanoLINEN) is a consortium of 7 European laboratories and Indian Institute of Toxicology Research (CSIR Laboratory) from India to strengthen the research ties in the area of Nanomaterial Toxicology. The goal of this project is to develop robust risk assessment methodologies that will be useful for the community manufacturing and using nano-products.


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