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Systematic review of the application of perinatal derivatives in animal models ...

Pichlsberger, Melanie; Jerman, Urška Dragin; Obradović, Hristina; Tratnjek, Larisa; Macedo, Ana Sofia; Mendes, Francisca; Fonte, Pedro; Hoegler, Anja

Knowledge of the beneficial effects of perinatal derivatives (PnD) in wound healing goes back to the early 1900s when the human fetal amniotic membrane served as a biological dressing to treat burns and skin ulcerations. Since the twenty-first century, isolated cells from perinatal tissues and their secretomes have gained increasing scientific interest, as they can be obtained non-invasively, have anti-inflamma...


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