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National survey of the rat hepatitis E virus in rodents in Spain, 2022 to 2023

Caballero-Gómez, J; Fajardo-Alonso, T; Ríos-Muñoz, L; Beato-Benítez, A; Casares-Jiménez, M; García-Bocanegra, I; Cuadrado-Matías, R; Martí-Marco, A

BackgroundRat hepatitis E virus (ratHEV) is an emerging virus causing acute and chronic hepatitis in humans. Rats are the main natural reservoir of this pathogen. Large-scale studies assessing ratHEV circulation in rodents in Spain are lacking.AimWe aimed to determine the prevalence of ratHEV in rats in Spain and evaluate potential transmission risk to humans.MethodsWe designed a cross-sectional nationwide stud...


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