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Regulation of stanniocalcin secretion by calcium and PTHrP in Gilthead Seabream...

Ruiz-Jarabo, I.; Gregorio, Silvia; Fuentes, Xoan

Calcium balance is of paramount importance for vertebrates. In fish, the endocrine modulators of calcium homeostasis include the stanniocalcin (STC), and some members of the parathyroid hormone (PTH) family, such as the PTH-related protein (PTHrP), acting as antagonists. STC is ubiquitously expressed in higher vertebrates. In turn, bony fish exhibit specific STC-producing glands named the corpuscles of Stannius...


High rates of intestinal bicarbonate secretion in seawater tilapia (Oreochromis...

Ruiz-Jarabo, I.; Gregorio, Silvia F.; Gaetano, P.; Trischitta, F.; Fuentes, Xoan

Osmoregulation in fish is a complex process that requires the orchestrated cooperation of many tissues. In fish facing hyperosmotic environments, the intestinal absorption of some monovalent ions and the secretion of bicarbonate are key processes to favor water absorption. In the present study, we showed that bicarbonate levels in the intestinal fluid are several fold higher in seawater than in freshwater accli...


PACAP system evolution and its role in melanophore function in teleost fish skin

CR Cardoso, Joao; C. Félix, Rute; Martins, Rute; M., Trindade; G Fonseca, Vera; Fuentes, Xoan; Power, Deborah

Pituitary adenylate cyclase-activating polypeptide (PACAP) administered to tilapia melanophores ex-vivo causes significant pigment aggregation and this is a newly identified function for this peptide in fish. The G-protein coupled receptors (GPCRs), adcyap1r1a (encoding Pac1a) and vipr2a (encoding Vpac2a), are the only receptors in melanophores with appreciable levels of expression and are significantly (p < 0....


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