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Mass Spectrometry-Based Proteomic and Metabolomic Profiling of Serum Samples fo...

Fernandes, Ana Filipa; Gonçalves, Luís Gafeira; Bento, Maria; Anjo, Sandra I.; Manadas, Bruno; Barroso, Clara; Villar, Miguel; Macedo, Rita

Tuberculosis (TB) is a transmissible disease listed as one of the 10 leading causes of death worldwide (10 million infected in 2019). A swift and precise diagnosis is essential to forestall its transmission, for which the discovery of effective diagnostic biomarkers is crucial. In this study, we aimed to discover molecular biomarkers for the early diagnosis of tuberculosis. Two independent cohorts comprising 29...


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