5 documents found, page 1 of 1
Factors associated with seropositivity for APGL-Iamong household contacts of le...
Wambier,Carlos Gustavo; Wambier,Sarah Perillo de Farias; Furini,Renata Bazan; Simão,João Carlos Lopes; Frade,Marco Andrey CiprianiAbstract: INTRODUCTION: Leprosy is mainly transmitted among family members who share genetic and ambient factors. The clinical form of leprosy in the index case and kinship could be risk factors for leprosy transmission. High antibody levels in household contacts (HC) in the absence of neural or skin lesions may characterize latent infection. This study aimed to evaluate the association between seropositivity f...
Oral coinfection can stress peripheral lymphocyte to inflammatory activity in l...
Motta,Ana Carolina Fragoso; Simão,João Carlos Lopes; Furini,Renata Bazan; Ferreira,Maria Aparecida Nunes; Palma,Patrícia Vianna BoniniINTRODUCTION: This study evaluated the intracellular profile of interleukin-2 (IL-2), interleukin-4 (IL-4), interleukin-10 (IL-10) and interferon-γ (IFN-γ) in peripheral blood mononuclear cells (PBMCs) from leprosy patients based on oral infections presence to determine whether these coinfections could be associated with pro-inflammatory activity in leprosy. METHODS: Leprosy patients regardless of clinical form...
Comparação entre microssatélites e o gene Ml MntH como alvos para a identificaç...
Cruz,Andrezza Furquim da; Furini,Renata Bazan; Roselino,Ana Maria FerreiraFUNDAMENTOS: PCR tem sido frequentemente utilizada no diagnóstico molecular da hanseníase. OBJETIVOS: comparar os resultados da PCR com 4 pares de primers específicos para Mycobacterium leprae, bem como os resultados da PCR à classificação operacional, segundo a OMS, de multibacilar (MB) e paucibacilar (PB) da hanseníase. MÉTODO: Vinte e oito amostras de DNA, extraído de biópsias congeladas de pele e de imprint...
Could leprosy reaction episodes be exacerbated by oral infections?
Motta,Ana Carolina Fragoso; Furini,Renata Bazan; Simão,João Carlos Lopes; Vieira,Mariana Bellini; Ferreira,Maria Aparecida NunesINTRODUCTION: This study evaluated whether leprosy reactions could be associated with oral infection. METHODS: Leprosy patients (n = 38) with (Group I) and without (Group II) oral infections were selected. Reactions were identified from the clinical and histopathological features associated with serum C-reactive protein (CRP) and10kDa interferon-gamma-induced protein (IP-10) levels, determined before and after ...
The recurrence of leprosy reactional episodes could be associated with oral chr...
Motta,Ana Carolina F.; Furini,Renata Bazan; Simão,João Carlos Lopes; Ferreira,Maria Aparecida Nunes; Komesu,Marilena C.; Foss,Norma T.The aim of this study was to determine whether the presence of leprosy reactional episodes could be associated with chronic oral infection. Thirty-eight leprosy patients were selected and divided into 2 groups: group I - 19 leprosy patients with oral infections, and group II - 19 leprosy patients without oral infections. Ten patients without leprosy, but presenting oral infections, were assigned to the control ...