2 documents found, page 1 of 1
Cloning of serine protease cDNAs from Crotalus durissus terrificus venom gland ...
Yonamine, Camila M.; Prieto-da-Silva, A. Rondinelly Brandão; Magalhães, Geraldo Santana.; Rádis-Baptista, Gandhi; Morganti, Ligia; Ambiel, F. C.Gyroxin is one of main serine proteases of Crotalus durissus terrificus venom, representing about 2% of the protein content in the crude venom. It is a 33 kDa glycoprotein with 3.8% by weight of sugar moiety. This toxin induces hemotoxicity in mice and a neurological condition called barrel rotation syndrome. In the present work, we report the molecular cloning of five new nucleotide sequences from a cDNA libra...
Rational selection of hidden epitopes for a molecularly imprinted electrochemic...
Silva, Matheus Siqueira; Tavares, Ana Patricia Moreira; Coelho, Luiz Felipe Leomil; Dias, Lígia Ely Morganti Ferreira; Chura-Chambi, Rosa MariaRational selection of predicted peptides to be employed as templates in molecular imprinting was carried out for the heat-denatured non-structural protein 1 (NS1) of dengue virus (DENV). Conservation analysis among 301 sequences of Brazilian isolates of DENV and zika virus (ZIKV) NS1 was carried out by UniProtKB, and peptide selection was based on in silico data of the conservational, structural and immunogenic...