Splenic artery syndrome (SAS) is described as a decrease in hepatic artery (HA) flow associated with increased flow in the splenic artery (SA). The present study aim was to identify predictive factors of SAS. A retrospective study was conducted in 70 patients, undergoing liver transplantation (LT) between 03/2010 until 08/2016. The case group (n=27) corresponded to the patients who developed SAS and the control...
Chronic inflammation is involved in the initiation and progression of various cancers, including liver cancer. The current study focuses on the characterization of the peripheral immune response in hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA) patients, before and after surgical procedure, in order to assess the effect of tumor resection in the immune system homeostasis and to determine possible p...
Hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA) represent the most common primary liver malignancies whose outcome is influenced by the immune response. In the present study, we evaluated the tumor-infiltrating leukocyte (TIL) populations in 21 HCC patients and 8 CCA patients by flow cytometry immediately after the surgical procedure. Moreover, CD4+ T cells, CD8+ T cells, monocytes, and macrophages ...
Background. Patients with liver cirrhosis may develop cirrhotic cardiomyopathy (CC), characterized by blunted contractile responsiveness to stress, diastolic dysfunction (DD), and electrophysiological abnormalities. It may adversely affect the long-term prognosis of these patients.Methods. We conducted a retrospective analysis of patients undergoing liver transplantation (LT) for cirrhosis from January 2012 to ...
Objectives: We review seven years of experience of surgical treatment of CD (Caroli Disease) in the HUC (Hospitais da Unversidade de Coimbra). Material and methods: Histopathology records from July 2000 to July 2007 were scanned CD. Patient files were retrieved and reviewed for demographic and clinical data, comorbidity and exam results. Previous diagnosis, medical treatments and other data pertaining to congen...
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