12 documents found, page 1 of 2
De novo colorectal cancer after liver and kidney transplantation–Microenvironme...
Oliveira, Rui Caetano; Silva, Edgar Tavares da; Abrantes, Ana Margarida; Antunes, Hugo; Teixeira, Paulo; Gomes, Ana; Martins, Ricardo; Furtado, EmanuelColorectal cancer (CRC) is a major health burden and may arise as a complication of solid organ transplantation. Our study aimed to assess the incidence of the CRC in kidney and liver transplanted patients at a tertiary and reference center and to describe their clinical and pathological features. Twelve patients, 10 men and two women, with a mean age of 60 years, composed our cohort, ten of them submitted to C...
Evaluation of bioenergetic and mitochondrial function in liver transplantation
Martins, Rui Miguel; Teodoro, João S.; Furtado, Emanuel; Rolo, Anabela Pinto; Palmeira, Carlos Marques; Tralhão, José GuilhermeBackground/Aims: We measured changes in mitochondrial function and bioenergetics that occur during ischemia/ reperfusion in fresh liver samples of patients undergoing liver transplantation. These variations correlated with markers of liver function and clinical outcome. Ischemia/reperfusion injury related to liver transplantation affects mitochondrial function and bioenergetics. Experimental studies were conduc...
Mild hypothermia during the reperfusion phase protects mitochondrial bioenerget...
Martins, Rui Miguel; Teodoro, João S.; Furtado, Emanuel; Oliveira, Rui Caetano; Tralhão, José Guilherme; Rolo, Anabela Pinto; Palmeira, Carlos MarquesThe organ preservation paradigm has changed following the development of new ways to preserve organs. The use of machine perfusion to preserve organs appears to have several advantages compared with conventional static cold storage. For liver transplants, the temperature control provided by machine perfusion improves organ preservation. In this experimental study, we measured the effects of different temperatur...
Functional impairment of circulating FcεRI+ monocytes and myeloid dendritic cel...
Martín-Sierra, Carmen; Martins, Ricardo; Laranjeira, Paula; Abrantes, A. Margarida; Oliveira, R. Caetano; Tralhão, J. Guilherme; Botelho, M. FilomenaBackground Hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA) represent the most common primary liver malignancies whose outcome is influenced by the immune response. Methods In this study, we have functionally characterized, by flow cytometry, circulating myeloid dendritic cells (mDCs) and FcεRI+ monocytes in a group of healthy individuals (n = 10) and in a group of patients with HCC (n = 19) and CCA ...
Personagem romântico de uma história revisada pela técnica jornalística
Mesquita, Ana Cecília; Cavalcante, Ana Mary; Accioly, Dante; Furtado, Emanuel; Guimarães, Erick; Moura, Fabiana; Nascimento, Fabíola; Paula, Giovana deGÓSSON, Agostinho. Personagem romântico de uma história revisada pela técnica jornalística. Revista Entrevista, Fortaleza, n. 6, p. 3-20, nov. 1996. Entrevista concedida a Ana Cecília Mesquita, Ana Mary Cavalcante, Dante Accioly, Emanuel Furtado, Erick Guimarães, Fabiana Moura, Fabíola Nascimento, Giovana de Paula, Ismael Furtado, Rodrigo de Almeida, Sérgio Ripardo e Silvia Bessa.; Era uma vez um menino dentuço...
A solista dos anjos interpreta a Psicologia da vida urbana
Mesquita, Ana Cecília; Cavalcante, Ana Mary; Accioly, Dante; Furtado, Emanuel; Guimarães, Erick; Moura, Fabiana; Paula, Giovana de; Furtado, IsmaelFREITAS, Kátia. A solista dos anjos interpreta a Psicologia da vida urbana. Revista Entrevista, Fortaleza,n. 6, p. 21-34, nov. 1996. Entrevista concedida a Ana Cecília Mesquita, Ana Mary Cavalcante, Dante Accioly, Emanuel Furtado, Erick Guimarães, Fabiana Moura, Fabíola Nascimento, Giovana de Paula, Ismael Furtado, Rodrigo de Almeida, Sérgio Ripardo e Silvia Bessa.; A palavra é bela. Kátia Maria sente a vida ne...
Pescador lança a rede no mar do passado e abre seu diário de bordo
Cavalcante, Ana Mary; Mesquita, Ana Cecília; Accioly, Dante; Furtado, Emanuel; Guimarães, Erick; Moura, Fabiana; Nascimento, Fabíola; Paula, Giovana deLIMA, José de. Pescador lança a rede no mar do passado e abre seu diário de bordo. Revista Entrevista, Fortaleza, n. 6, p. 35-47, nov. 1996. Entrevista concedida a Ana Mary Cavalcante, Ana Cecília Mesquita, Dante Accioly, Emanuel Furtado, Erick Guimarães, Fabiana Moura, Fabíola Nascimento, Giovana de Paula, Ismael Furtado, Rodrigo de Almeida, Sérgio Ripardo e Sílvia Bessa.; Pele morena, chapéu de palha, sobranc...
A tênue fronteira entre a objetividade jornalística e a subjetividade teatral
Mesquita, Ana Cecília; Cavalcante, Ana Mary; Accioly, Dante; Furtado, Emanuel; Guimarães, Erick; Moura, Fabiana; Nascimento, Fabíola; Paula, Giovana deCAMPOS, Eduardo. A tênue fronteira entre a objetividade jornalística e a subjetividade teatral. Revista Entrevista, Fortaleza, n. 6, p. 48-65, nov. 1996. Entrevista concedida a Ana Cecília Mesquita, Ana Mary Cavalcante, Dante Accioly, Emanuel Furtado, Erick Guimarães, Fabiana Moura, Fabíola Nascimento, Giovana de Paula, Ismael Furtado, Rodrigo de Almeida, Sérgio Ripardo e Silvia Bessa.; Último sobrevivente dos ...
Recent insights into mitochondrial targeting strategies in liver transplantation
Martins, Rui Miguel; Teodoro, João Soeiro; Furtado, Emanuel; Rolo, Anabela Pinto; Palmeira, Carlos Marques; Tralhão, José GuilhermeIschemia/reperfusion (I/R) injury in liver transplantation can disrupt the normal activity of mitochondria in the hepatic parenchyma. This potential dysfunction of mitochondria after I/R injury could be responsible for the initial poor graft function or primary nonfunction observed after liver transplantation. Thus, determining the mechanisms that lead to human hepatic mitochondrial dysfunction might contribute...
Addition of Berberine to Preservation Solution in an Animal Model of Ex Vivo Li...
Martins, Rui Miguel; Rolo, Anabela Pinto; Teodoro, João Soeiro; Furtado, Emanuel; Oliveira, Rui Caetano; Tralhão, José GuilhermeLiver transplantation is a therapeutic regimen to treat patients with non-malignant end-stage liver diseases and malignant tumors of hepatic origin. The ischemia/reperfusion (I/R) injury in liver transplantation is associated with disruption of mitochondrial function in the hepatic parenchyma. Several studies have been conducted in animal models to identify pharmacological therapeutic strategies to minimize the...