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Quality of life in hospitalized COVID-19 patients: The role of psychosocial, in...

Pereira, M. Graça; Vilaça, Margarida; Santos, Martim; Carvalho, Sandra; Leite, Jorge; Santos Silva, André; Consentino, Marco; Marino, Franca

Introduction: A significant proportion of COVID-19 survivors continues to suffer from persistent physical and psychological sequelae after hospital discharge. Materials and methods: This cross-sectional study aimed to analyze the roles of psychosocial, inflammatory, and dopaminergic pathways in the relationship between posttraumatic stress symptoms (PTSS), rumination, and quality of life (QoL) in patients hospi...


Beyond COVID-19 infection: cognitive and emotional pathways between posttraumat...

Vilaça, Margarida; Carvalho, Sandra; Leite, Jorge; Leite, Fernanda; Pereira, M. Graça

Background: Hospitalization during the COVID-19 pandemic has been linked with increased psychological distress, cognitive impairment, and reduced quality of life (QoL). Posttraumatic stress symptoms (PTSS) and rumination may significantly influence QoL outcomes, yet the mechanisms underlying these effects remain poorly understood. Based on the Cognitive Aging Model, this study examines the mediating effects of ...


Integrated care in atrial fibrillation: A multidisciplinary approach to improve...

Machado, Ana Mónica; Leite, Fernanda; Pereira, M. Graça

Background: Atrial fibrillation (AF) is the most common arrhythmia globally, associated with serious complications such as stroke and heart failure, as well as significant impacts on patients' quality of life. Objectives: This theoretical article explores the role of integrated care in the management of AF, highlighting the need for a multidisciplinary approach that goes beyond rhythm and heart rate control. Me...


Incerteza e literacia em saúde na fibrilação auricular: Implicações e estratégi...

Machado, Ana Mónica Macedo Mendonça; Leite, Fernanda; Pereira, M. Graça

A fibrilação auricular é uma condição crónica complexa, cuja gestão eficaz exige uma abordagem que vá além do controlo eletrofisiológico, integrando dimensões psicossociais frequentemente negligenciadas. Este capítulo analisa o papel da incerteza e da literacia em saúde na vivência da fibrilação auricular e o seu impacto na qualidade de vida dos doentes. A incerteza, entendida como a dificuldade em compreender,...


Beyond the beats: a systematic review of the underlying inflammatory pathways b...

Machado, Ana Mónica Macedo Mendonça; Ferraz, Ana Sofia; Pereira, M. Graça; Leite, Fernanda

Atrial fibrillation (AF) and cognitive decline represent significant health challenges with increasing prevalence and significant socioeconomic implications. Emerging evidence suggests a potential link between AF and cognitive decline, including dementia and Alzheimer’s disease, although the underlying mechanisms remain incompletely understood. Inflammation has emerged as a key mediator in cardiovascular and ne...


Fibrilação auricular: desafios e implicações na qualidade de vida e declínio co...

Machado, Ana Mónica Macedo Mendonça; Leite, Fernanda; Pereira, M. Graça

A fibrilação auricular é a arritmia cardíaca mais comum na prática clínica, afetando milhões de pessoas globalmente. Caracterizada pela desorganização da atividade elétrica nas aurículas, resulta em contrações auriculares ineficazes, muitas vezes rápidas, o que pode levar a complicações graves, como acidente vascular cerebral, insuficiência cardíaca e morte. Devido à sua prevalência crescente, especialmente em ...


Impact of quality and type of anticoagulant treatment, and In ammatory biomarke...

Machado, Ana Mónica; Leite, Fernanda; Pereira, M. Graça

Background: Owing to increasing worldwide life expectancy, the step rise in the prevalence of atrial fibrillation (AF) represents an urgent public health issue. Indeed, AF can severely affect a patient's quality of life (QoL) since it is associated with serious outcomes, such as stroke, cardiac failure, and cognitive impairment/dementia, resulting in increased morbidity and mortality and a burden for health-car...


Using BIM to improve building energy efficiency: a scientometric and systematic...

Pereira, Vítor; Santos, José; Leite, Fernanda; Escórcio, Patrícia

The Architecture, Engineering, Construction, and Operations (AECO) sector is responsible for a great pro portion of the global energy consumption and associated environmental impacts. On this front, and from a sustainability improvement perspective, the use of Building Information Modelling (BIM) capabilities could represent an opportunity to improve these impacts in all steps of a building’s life. The main pur...


Subjects at Risk for Genetic Late-Onset Neurological Diseases: Objective Knowledge

Leite, Ângela; Leite, Fernanda; Dinis, Maria Alzira Pimenta

BACKGROUND/AIMS: This study addresses the objective knowledge about the disease of subjects at risk for 3 genetic late-onset neurological diseases (LOND): familial amyloid polyneuropathy (FAP) TTR V30M, Huntington disease (HD), and Machado-Joseph disease (MJD). METHODS: Subjects at risk for FAP, HD, and MJD submitted to genetic counseling to know their status (carrier or non-carrier) and subjects at risk for he...


Influência do fenótipo HLA e da razão CD4/CD8 na expressão da Doença hepática e...

Cruz, Eugénia; Porto, Graça; Fraga, José; Moreira, R.; Castro, D.; Alves, Helena; Leite, Fernanda; Bravo, Fernanda; Lacerda, Rosa; Cabeda, José M. B.


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